Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL3 | Q96JM7 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | PIM1 | P11309 | 1/20 | 0.31 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.31 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.31 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.31 |
| ▸ | NCF1 | P14598 | 1/20 | 0.30 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19089531 | 0.92 | L3MBTL3 (0.37) | L3MBTL3L3MBTL1ALDH1A1KDM1APIM1 | |
| SCHEMBL24541593 | 0.87 | CHRM2 (0.33) | ALDH1A1HRH3CHRM2CHRM1TP53 | |
| SCHEMBL26818871 | 0.84 | HRH3 (0.36) | L3MBTL3L3MBTL1KDM1AHRH3TLR9 | |
| SCHEMBL21361601 | 0.83 | SIGMAR1 (0.41) | HRH3CHRM2CHRM1TP53TSHR | |
| SCHEMBL134732 | 0.83 | L3MBTL3 (0.39) | L3MBTL3L3MBTL1ALDH1A1HRH3PIM1 | |
| SCHEMBL23269621 | 0.82 | L3MBTL3 (0.38) | L3MBTL3L3MBTL1ALDH1A1HRH3PIM1 | |
| SCHEMBL26042916 | 0.80 | L3MBTL3 (0.47) | L3MBTL3L3MBTL1ALDH1A1KDM1APIM1 | |
| SCHEMBL19119393 | 0.79 | L3MBTL3 (0.46) | L3MBTL3L3MBTL1ALDH1A1 | |
| SCHEMBL26022672 | 0.79 | L3MBTL3 (0.46) | L3MBTL3L3MBTL1ALDH1A1 | |
| SCHEMBL22456332 | 0.79 | L3MBTL3 (0.39) | L3MBTL3L3MBTL1ALDH1A1HRH3PIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021160087-A1 | QUINOLYL PHOSPHINE OXIDE COMPOUND, AND COMPOSITION AND APPLICATION THEREOF | 贝达药业股份有限公司 | 2021-08-19 | — | — | WO | disclosed |