Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 7/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | XBP1 | P17861 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21090669 | 0.81 | L3MBTL1 (0.54) | TP53MAPTMEN1KMT2AHTT | |
| SCHEMBL19089701 | 0.79 | CES2 (0.46) | MEN1KMT2AALDH1A1LMNAGAA | |
| SCHEMBL18666197 | 0.79 | MAPT (0.52) | TP53MAPTMEN1KMT2AHTT | |
| SCHEMBL18665944 | 0.78 | TP53 (0.56) | TP53MAPTMEN1KMT2AHTT | |
| SCHEMBL28825701 | 0.77 | L3MBTL1 (0.59) | TP53MAPTMEN1KMT2AHTT | |
| SCHEMBL9235084 | 0.77 | MEN1 (0.55) | TP53MAPTMEN1KMT2AHTT | |
| SCHEMBL5207667 | 0.75 | TP53 (0.60) | TP53MAPTMEN1KMT2AHTT | |
| SCHEMBL14498323 | 0.75 | TP53 (0.60) | TP53MAPTMEN1KMT2AHTT | |
| SCHEMBL5207675 | 0.75 | TP53 (0.60) | TP53MAPTMEN1KMT2AHTT | |
| SCHEMBL5204156 | 0.74 | ALDH1A1 (0.63) | TP53MAPTMEN1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10018619-B2 | Compounds and method of identifying, synthesizing, optimizing and profiling protein modulators | HMI Medical Innovations, LLC (US) | 2018-07-10 | — | — | US | disclosed |
| US-20170191986-A1 | Compounds and Method of Identifying, Synthesizing, Optimizing and Profiling Protein Modulators | HMI Medical Innovations, LLC | 2017-07-06 | — | — | US | disclosed |