SCHEMBL19089985

SCHEMBL19089985

O=C(OC1C(O)[C@@H](Sc2ccccc2)OC(CO)[C@@H]1OCc1ccccc1)c1ccccc1

nearest known ligand 0.59

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
LGALS3 P17931 9/20 0.59
LGALS9 O00182 8/20 0.59
LGALS1 P09382 8/20 0.59
LGALS7; LGALS7B P47929 6/20 0.59
LGALS8 O00214 6/20 0.47
NT5E P21589 1/20 0.42
TACR2 P21452 1/20 0.41
LGALS2 P05162 2/20 0.39
LGALS4 P56470 2/20 0.39
SLC6A2 P23975 1/20 0.39
SELP P16109 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24107976 0.92 LGALS9 (0.56) LGALS3LGALS9LGALS1LGALS7; LGALS7BLGALS8
SCHEMBL3659771 0.92 LGALS9 (0.53) LGALS3LGALS9LGALS1LGALS7; LGALS7BLGALS8
SCHEMBL17309342 0.86 LGALS3 (0.57) LGALS3LGALS9LGALS1LGALS7; LGALS7BLGALS8
SCHEMBL19090197 0.86 LGALS3 (0.80) LGALS3LGALS9LGALS1LGALS7; LGALS7BLGALS8
SCHEMBL17309354 0.86 LGALS3 (0.80) LGALS3LGALS9LGALS1LGALS7; LGALS7BLGALS8
SCHEMBL22500214 0.85 LGALS3 (0.49) LGALS3LGALS9LGALS1LGALS7; LGALS7BLGALS8
SCHEMBL19674473 0.83 LGALS3 (0.58) LGALS3LGALS9LGALS1LGALS7; LGALS7BLGALS8
SCHEMBL19674440 0.83 LGALS3 (0.58) LGALS3LGALS9LGALS1LGALS7; LGALS7BLGALS8
SCHEMBL21851777 0.83 SLC6A2 (0.53) LGALS3LGALS9LGALS1LGALS7; LGALS7BLGALS8
SCHEMBL24086075 0.83 SLC6A2 (0.53) LGALS3LGALS9LGALS1LGALS7; LGALS7BLGALS8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10806746-B2 Di- and tri-cationic glycosylated antitumor ether lipids, L-gucosylated gaels and rhamnose-linked gaels as cytotoxic agents against epithelial cancer cells and cancer stem cells THE UNIV OF MANITOBA (CA) 2020-10-20 US disclosed
US-20170189438-A1 DI- and Tri-Cationic Glycosylated Antitumor Ether Lipids, L-Gucosylated Gaels and Rhamnose-Linked Gaels as Cytotoxic Agents Against Epithelial Cancer Cells and Cancer Stem Cells THE UNIV OF MANITOBA (CA) 2017-07-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170189438-A1 DI- and Tri-Cationic Glycosylated Antitumor Ether Lipids, L-Gucosylated Gaels and Rhamnose-Linked Gaels as Cytotoxic Agents Against Epithelial Cancer Cells and Cancer Stem Cells UGCG, PNLIP, B3GAT3 LGALS3 31/4885LGALS9 176/4885LGALS1 59/4885
US-10806746-B2 Di- and tri-cationic glycosylated antitumor ether lipids, L-gucosylated gaels and rhamnose-linked gaels as cytotoxic agents against epithelial cancer cells and cancer stem cells PNLIP, UGCG, LIPC LGALS3 30/4885LGALS9 152/4885LGALS1 56/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.