Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | F2 | P00734 | 2/20 | 0.60 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.60 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.60 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 6/20 | 0.52 |
| ▸ | CA2 | P00918 | 6/20 | 0.52 |
| ▸ | CA5A | P35218 | 6/20 | 0.52 |
| ▸ | CA5B | Q9Y2D0 | 6/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL863312 | 0.87 | KMT2A (0.70) | KMT2AALDH1A1F2PRSS1PRSS2 | |
| SCHEMBL12705857 | 0.87 | KMT2A (0.70) | KMT2AALDH1A1F2PRSS1PRSS2 | |
| SCHEMBL10000728 | 0.87 | KMT2A (0.70) | KMT2AALDH1A1F2PRSS1PRSS2 | |
| SCHEMBL5960692 | 0.87 | KMT2A (0.70) | KMT2AALDH1A1F2PRSS1PRSS2 | |
| SCHEMBL7427394 | 0.86 | KMT2A (0.68) | KMT2AALDH1A1F2PRSS1PRSS2 | |
| SCHEMBL1362019 | 0.84 | KMT2A (0.70) | KMT2AALDH1A1F2PRSS1PRSS2 | |
| SCHEMBL10415674 | 0.83 | KMT2A (0.65) | KMT2AALDH1A1F2PRSS1PRSS2 | |
| SCHEMBL23124424 | 0.83 | KMT2A (0.68) | KMT2AALDH1A1F2PRSS1PRSS2 | |
| SCHEMBL412452 | 0.83 | KMT2A (0.68) | KMT2AALDH1A1F2PRSS1PRSS2 | |
| SCHEMBL19121771 | 0.83 | KMT2A (0.68) | KMT2AALDH1A1F2PRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017115205-A1 | SUBSTITUTED 3-AZABICYCLO[3.1.0]HEXANES AS KETOHEXOKINASE INHIBITORS | PFIZER INC. (US) | 2017-07-06 | — | — | WO | disclosed |