Sugi Predict

Sugi Predict / Compounds / SCHEMBL5960692

SCHEMBL5960692

SCHEMBL5960692

CC1(C)[C@H]2CC[C@]1(CS(C)(=O)=O)C(=O)C2

nearest known ligand 0.70

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 3/20 0.70
▸ ALDH1A1 P00352 2/20 0.65
▸ F2 P00734 2/20 0.63
▸ PRSS1 P07477 2/20 0.63
▸ PRSS2 P07478 2/20 0.63
▸ PRSS3 P35030 2/20 0.63
▸ MEN1 O00255 2/20 0.60
▸ SMN1; SMN2 Q16637 1/20 0.60
▸ CYP1A2 P05177 1/20 0.59
▸ CYP2C19 P33261 1/20 0.59
▸ KDM4E B2RXH2 1/20 0.56
▸ CA1 P00915 6/20 0.54
▸ CA2 P00918 6/20 0.54
▸ CA5A P35218 6/20 0.54
▸ CA5B Q9Y2D0 6/20 0.54
▸ L3MBTL1 Q9Y468 1/20 0.54
▸ GAA P10253 1/20 0.53
▸ PKM P14618 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12705857 1.00 KMT2A (0.70) KMT2AALDH1A1F2PRSS1PRSS2
SCHEMBL10000728 1.00 KMT2A (0.70) KMT2AALDH1A1F2PRSS1PRSS2
SCHEMBL863312 1.00 KMT2A (0.70) KMT2AALDH1A1F2PRSS1PRSS2
SCHEMBL19098992 0.87 KMT2A (0.67) KMT2AALDH1A1F2PRSS1PRSS2
SCHEMBL1362019 0.87 KMT2A (0.70) KMT2AALDH1A1F2PRSS1PRSS2
SCHEMBL10415674 0.86 KMT2A (0.65) KMT2AALDH1A1F2PRSS1PRSS2
SCHEMBL23124424 0.85 KMT2A (0.68) KMT2AALDH1A1F2PRSS1PRSS2
SCHEMBL1500774 0.85 KMT2A (0.68) KMT2AALDH1A1F2PRSS1PRSS2
SCHEMBL467203 0.85 KMT2A (0.68) KMT2AALDH1A1F2PRSS1PRSS2
SCHEMBL12706679 0.85 KMT2A (0.68) KMT2AALDH1A1F2PRSS1PRSS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9856254-B2 Alkoxy substituted imidazoquinolines 3M INNOVATIVE PROPERTIES COMPANY (US) 2018-01-02 — — US disclosed
US-20160280707-A1 ALKOXY SUBSTITUTED IMIDAZOQUINOLINES 3M INNOVATIVE PROPERTIES CO (US) 2016-09-29 — — US disclosed
US-20160280707-A1 ALKOXY SUBSTITUTED IMIDAZOQUINOLINES 3M INNOVATIVE PROPERTIES CO (US) 2016-09-29 — — US disclosed
US-9365567-B2 Alkoxy substituted imidazoquinolines 3M INNOVATIVE PROPERTIES COMPANY (US) 2016-06-14 — — US disclosed
US-9365567-B2 Alkoxy substituted imidazoquinolines 3M INNOVATIVE PROPERTIES COMPANY (US) 2016-06-14 — — US disclosed
US-9145410-B2 Pyrazolopyridines and analogs thereof 3M INNOVATIVE PROPERTIES COMPANY (US) 2015-09-29 — — US disclosed
EP-1673087-B1 ALKOXY SUBSTITUTED IMIDAZOQUINOLINES 3M INNOVATIVE PROPERTIES CO (US) 2015-05-13 — — EP disclosed
US-20150023990-A1 ALKOXY SUBSTITUTED IMIDAZOQUINOLINES 3M INNOVATIVE PROPERTIES COMPANY 2015-01-22 — — US disclosed
US-20150023990-A1 ALKOXY SUBSTITUTED IMIDAZOQUINOLINES 3M INNOVATIVE PROPERTIES COMPANY 2015-01-22 — — US disclosed
US-8871782-B2 Alkoxy substituted imidazoquinolines 3M INNOVATIVE PROPERTIES COMPANY (US) 2014-10-28 — — US disclosed
US-7598382-B2 Aryl substituted imidazoquinolines COLEY PHARMACEUTICAL GROUP, INC. (US) 2009-10-06 — — US disclosed
US-7598382-B2 Aryl substituted imidazoquinolines COLEY PHARMACEUTICAL GROUP, INC. (US) 2009-10-06 — — US disclosed
US-7544697-B2 Pyrazolopyridines and analogs thereof COLEY PHARMACEUTICAL GROUP, INC. (US) 2009-06-09 — — US disclosed
US-20090075980-A1 Pyrazolopyridines and Analogs Thereof COLEY PHARMACEUTICAL GROUP, INC. (US) 2009-03-19 — — US disclosed
US-20070167476-A1 Piperazine, [1,4]Diazepane, [1,4]Diazocane, and [1,5]Diazocane fused imidazo ring compounds 3M INNOVATIVE PROPERTIES COMPANY 2007-07-19 — — US disclosed
US-20070099901-A1 Hydroxylamine and oxime substituted imidazoquinolines, imidazopyridines, and imidazonaphthyridines 3M INNOVATIVE PROPERTIES COMPANY (US) 2007-05-03 — — US disclosed
US-20070099955-A1 3-PIPERIDINYLISOCHROMAN-5-OLS AS DOPAMINE AGONISTS AVENTIS PHARMACEUTICALS INC. (US) 2007-05-03 — — US disclosed
US-20070099955-A1 3-PIPERIDINYLISOCHROMAN-5-OLS AS DOPAMINE AGONISTS AVENTIS PHARMACEUTICALS INC. (US) 2007-05-03 — — US disclosed
US-20070060754-A1 Alkoxy substituted imidazoquinolines 3M INNOVATIVE PROPERTIES COMPANY 2007-03-15 — — US disclosed
US-20070060754-A1 Alkoxy substituted imidazoquinolines 3M INNOVATIVE PROPERTIES COMPANY 2007-03-15 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150023990-A1 ALKOXY SUBSTITUTED IMIDAZOQUINOLINES IL2, IFNG, IRF3 KMT2A 2789/4885ALDH1A1 918/4885F2 4238/4885
US-20070060754-A1 Alkoxy substituted imidazoquinolines IL2, IFNG, IRF3 KMT2A 2789/4885ALDH1A1 918/4885F2 4238/4885
US-20070167476-A1 Piperazine, [1,4]Diazepane, [1,4]Diazocane, and [1,5]Diazocane fused imidazo ring compounds IL4, IL2, IL5 KMT2A 2219/4885ALDH1A1 401/4885F2 2876/4885
US-20160280707-A1 ALKOXY SUBSTITUTED IMIDAZOQUINOLINES IL2, IFNG, IRF3 KMT2A 2789/4885ALDH1A1 918/4885F2 4238/4885
US-20090075980-A1 Pyrazolopyridines and Analogs Thereof IL4, IL4I1, IL2 KMT2A 2980/4885ALDH1A1 1406/4885F2 1710/4885
US-20070099955-A1 3-PIPERIDINYLISOCHROMAN-5-OLS AS DOPAMINE AGONISTS DRD3, DRD2, DRD4 KMT2A 2239/4885ALDH1A1 241/4885F2 2304/4885
US-20070099901-A1 Hydroxylamine and oxime substituted imidazoquinolines, imidazopyridines, and imidazonaphthyridines IFNG, IRF3, IDO1 KMT2A 1578/4885ALDH1A1 679/4885F2 4369/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.