Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METTL3 | Q86U44 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | CLEC4M | Q9H2X3 | 1/20 | 0.47 |
| ▸ | CDC25B | P30305 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.45 |
| ▸ | GABRP | O00591 | 1/20 | 0.44 |
| ▸ | GABRD | O14764 | 1/20 | 0.44 |
| ▸ | PDE5A | O76074 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL543898 | 0.83 | METTL3 (0.50) | METTL3KDM4ETSHRNPC1RAB9A | |
| SCHEMBL31719176 | 0.83 | METTL3 (0.50) | METTL3KDM4ETSHRNPC1RAB9A | |
| Hydrochloric Acid SCHEMBL30715238 | 0.82 | METTL3 (0.52) | METTL3KDM4ETSHRNPC1RAB9A | |
| SCHEMBL28267337 | 0.79 | KDM4E (0.48) | METTL3ALDH1A1KDM4EHSD17B10NPC1 | |
| SCHEMBL30591278 | 0.79 | METTL3 (0.48) | METTL3ESR1IDO1 | |
| SCHEMBL22886579 | 0.79 | BRAF (0.52) | METTL3ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL4155814 | 0.79 | ALDH1A1 (0.50) | METTL3ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL11577717 | 0.79 | KMT2A (0.56) | ALDH1A1MEN1KMT2AKDM4ETSHR | |
| SCHEMBL7241231 | 0.79 | DHFR (0.57) | METTL3L3MBTL1ESR1IDO1 | |
| SCHEMBL2301267 | 0.79 | ESR1 (0.50) | METTL3ALDH1A1MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020186220-A1 | COMPOUNDS AS INHIBITORS OF MACROPHAGE MIGRATION INHIBITORY FACTOR | IMMUNOPHAGE BIOMEDICAL CO., LTD. (CN) | 2020-09-17 | — | — | WO | disclosed |
| CN-111132964-A | Glucocorticoid receptor modulators | 欧瑞克制药公司 | 2020-05-08 | — | — | CN | disclosed |
| EP-3400223-A1 | MICROBIOCIDAL OXADIAZOLE DERIVATIVES | Syngenta Participations AG (CH) | 2018-11-14 | — | — | EP | disclosed |
| WO-2017118689-A1 | MICROBIOCIDAL OXADIAZOLE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2017-07-13 | — | — | WO | disclosed |