Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | METTL3 | Q86U44 | 3/20 | 0.47 |
| ▸ | KIT | P10721 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.43 |
| ▸ | NOS1 | P29475 | 3/20 | 0.42 |
| ▸ | AXL | P30530 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31719176 | 0.83 | METTL3 (0.50) | KDM4EHPGDMETTL3KITNPC1 | |
| SCHEMBL543898 | 0.83 | METTL3 (0.50) | KDM4EHPGDMETTL3KITNPC1 | |
| Hydrochloric Acid SCHEMBL30715238 | 0.82 | METTL3 (0.52) | KDM4EHPGDMETTL3KITNPC1 | |
| SCHEMBL19100359 | 0.79 | METTL3 (0.58) | KDM4EALDH1A1HSD17B10METTL3NPC1 | |
| SCHEMBL2587386 | 0.79 | METTL3 (0.53) | METTL3KITTRPV1 | |
| SCHEMBL30285533 | 0.76 | NOS1 (0.52) | ALDH1A1HPGDMETTL3KITNPC1 | |
| SCHEMBL260364 | 0.76 | NOS1 (0.52) | ALDH1A1HPGDMETTL3KITNPC1 | |
| SCHEMBL7496719 | 0.76 | KDM4E (0.54) | KDM4EALDH1A1HPGDHSD17B10NPC1 | |
| SCHEMBL7379757 | 0.74 | NOS1 (0.50) | HPGDMETTL3KITNPC1IDO1 | |
| Hydrochloric Acid SCHEMBL1056437 | 0.74 | NOS1 (0.50) | ALDH1A1HPGDMETTL3KITNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109180687-A | A kind of preparation method of auspicious Kappa step intermediate | 山东轩德医药科技有限公司 | 2019-01-11 | — | — | CN | claimed |