Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 13/20 | 0.44 |
| ▸ | KDM5A | P29375 | 10/20 | 0.44 |
| ▸ | KDM5B | Q9UGL1 | 10/20 | 0.44 |
| ▸ | KDM4A | O75164 | 5/20 | 0.44 |
| ▸ | KDM2B | Q8NHM5 | 3/20 | 0.39 |
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19101675 | 0.88 | KDM4C (0.52) | KDM4CKDM5AKDM5BKDM4AKDM2B | |
| SCHEMBL19101736 | 0.87 | KDM4A (0.53) | KDM4CKDM4APHF8 | |
| SCHEMBL19101685 | 0.85 | PHF8 (0.48) | KDM4CKDM5AKDM5BKDM4AKDM2B | |
| SCHEMBL16033534 | 0.83 | KDM5A (0.65) | KDM4CKDM5AKDM5BKDM4AKDM2B | |
| SCHEMBL19101706 | 0.75 | KDM5A (0.67) | KDM4CKDM5AKDM5BKDM4AKDM2B | |
| SCHEMBL16075704 | 0.74 | KDM5A (0.76) | KDM4CKDM5AKDM5BKDM4AKDM2B | |
| SCHEMBL16033844 | 0.73 | KDM4C (0.77) | KDM4CKDM5AKDM5BKDM4AKDM2B | |
| SCHEMBL16032896 | 0.72 | KDM4C (0.77) | KDM4CKDM5AKDM5BKDM4AKDM2B | |
| SCHEMBL19139044 | 0.71 | KDM2B (0.47) | KDM4CKDM5AKDM5BKDM4AKDM2B | |
| SCHEMBL16033753 | 0.70 | KDM5A (0.60) | KDM4CKDM5AKDM5BKDM4AKDM2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9701657-B2 | Histone demethylase inhibitors | CELGENE QUANTICEL RESEARCH, INC. (US) | 2017-07-11 | — | — | US | disclosed |