Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.46 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | PPARA | Q07869 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | PPARD | Q03181 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8257865 | 0.93 | PDK2 (0.54) | PDK2L3MBTL1LTB4RLTB4R2KDM4E | |
| SCHEMBL17572343 | 0.87 | PDK2 (0.47) | PDK2KDM4EALDH1A1GPR119DRD2 | |
| SCHEMBL13886642 | 0.85 | LTA4H (0.59) | PDK2KDM4EALDH1A1PPARASMN1; SMN2 | |
| SCHEMBL29607396 | 0.85 | ALDH1A1 (0.47) | PDK2KDM4EALDH1A1PPARAKMT2A | |
| SCHEMBL19564642 | 0.84 | FDPS (0.53) | PDK2L3MBTL1KDM4EALDH1A1MEN1 | |
| SCHEMBL25725297 | 0.82 | RAB9A (0.44) | PDK2L3MBTL1ALDH1A1MEN1KMT2A | |
| SCHEMBL21163143 | 0.82 | PDK2 (0.45) | PDK2L3MBTL1KDM4EALDH1A1GPR119 | |
| SCHEMBL12177889 | 0.82 | PDK2 (0.43) | PDK2KDM4EALDH1A1PPARAPPARD | |
| SCHEMBL21601541 | 0.81 | PDK2 (0.54) | PDK2L3MBTL1KDM4EPPARAKCNH2 | |
| SCHEMBL19975771 | 0.81 | PDK2 (0.42) | PDK2KDM4EALDH1A1GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3190111-B1 | PYRAZOLO[3,4-C]PYRIDINE DERIVATIVES | CSPC ZHONGQI PHARMACEUTICAL TECH SHIJIAZHUANG CO LTD (CN) | 2020-05-06 | — | — | EP | disclosed |
| EP-3190111-A1 | PYRAZOLO[3,4-C]PYRIDINE DERIVATIVES | CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang) Co., Ltd. (CN) | 2017-07-12 | — | — | EP | disclosed |