Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 4/20 | 0.40 |
| ▸ | CXCR3 | P49682 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.35 |
| ▸ | RHOC | P08134 | 3/20 | 0.34 |
| ▸ | RHOA | P61586 | 3/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.34 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | STS | P08842 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TACR1 | P25103 | 1/20 | 0.33 |
| ▸ | ACP1 | P24666 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4276573 | 0.83 | CYP1A2 (0.43) | EPHX2CXCR3ALDH1A1RHOCRHOA | |
| SCHEMBL4276575 | 0.83 | CYP1A2 (0.43) | EPHX2CXCR3ALDH1A1RHOCRHOA | |
| SCHEMBL8374022 | 0.77 | CYP1A2 (0.40) | EPHX2CXCR3STSTACR1 | |
| SCHEMBL6863335 | 0.75 | STS (0.56) | EPHX2CXCR3STSTACR1 | |
| SCHEMBL4272965 | 0.74 | HSD17B10 (0.52) | EPHX2CXCR3ALDH1A1HCRTR1HCRTR2 | |
| SCHEMBL4272968 | 0.74 | HSD17B10 (0.52) | EPHX2CXCR3ALDH1A1HCRTR1HCRTR2 | |
| SCHEMBL4276665 | 0.74 | HSD17B10 (0.52) | EPHX2CXCR3ALDH1A1HCRTR1HCRTR2 | |
| SCHEMBL4278127 | 0.74 | CXCR3 (0.56) | EPHX2CXCR3ALDH1A1NAMPTRHOC | |
| SCHEMBL22019439 | 0.74 | CXCR3 (0.46) | EPHX2CXCR3ALDH1A1NAMPTHCRTR1 | |
| SCHEMBL1445327 | 0.74 | LMNA (0.52) | EPHX2CXCR3ALDH1A1NAMPTRHOC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3189839-A1 | N-PIPERIDINYL ACETAMIDE DERIVATIVES AS CALCIUM CHANNEL BLOCKERS | Taro Pharmaceuticals Inc. (CA) | 2017-07-12 | — | — | EP | disclosed |