SCHEMBL19117014

SCHEMBL19117014

C#CCOC(=O)C(C)(F)C(=O)O

nearest known ligand 0.36

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ACHE P22303 2/20 0.36
NPC1 O15118 1/20 0.35
POLB P06746 1/20 0.33
TSHR P16473 2/20 0.32
SLC1A3 P43003 1/20 0.31
SLC1A2 P43004 1/20 0.31
SLC1A1 P43005 1/20 0.31
CYP1A2 P05177 1/20 0.30
CHRM2 P08172 1/20 0.30
CHRM4 P08173 1/20 0.30
CHRM5 P08912 1/20 0.30
CYP2D6 P10635 1/20 0.30
CHRM1 P11229 1/20 0.30
NFKB1 P19838 1/20 0.30
CHRM3 P20309 1/20 0.30
THPO P40225 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19105217 0.90 NPC1 (0.38) ACHENPC1POLBTSHRCYP1A2
SCHEMBL6972555 0.80 NPC1 (0.37) ACHENPC1POLBTSHRSLC1A3
SCHEMBL19116958 0.79 MMP1 (0.33)
SCHEMBL19117841 0.78 POLB (0.34) ACHENPC1POLBTSHR
SCHEMBL2478567 0.77 NPC1 (0.41) ACHENPC1POLBTSHRSLC1A3
SCHEMBL27657800 0.77 NPC1 (0.41) ACHENPC1POLBTSHRSLC1A3
SCHEMBL21228301 0.77 NPC1 (0.41) ACHENPC1POLBTSHRSLC1A3
SCHEMBL29151602 0.77 NPC1 (0.39) NPC1POLBTSHRSLC1A3SLC1A2
Trifluoroacetic Acid SCHEMBL4666819 0.76 NOS1 (0.35) ACHENPC1
SCHEMBL3903232 0.75 MMP8 (0.43) POLBTSHRCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170200976-A1 NON-AQUEOUS ELECTROLYTIC SOLUTION AND NON-AQUEOUS ELECTROLYTE SECONDARY BATTERY USING THE SAME MITSUBISHI CHEMICAL CORPORATION (JP) 2017-07-13 US disclosed