Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | POLA1 | P09884 | 1/20 | 0.56 |
| ▸ | POLD1 | P28340 | 1/20 | 0.56 |
| ▸ | TK1 | P04183 | 7/20 | 0.52 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | ALB | P02768 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL154177 | 0.90 | POLB (0.65) | POLBPOLA1POLD1TK1BCHE | |
| Triphosphate SCHEMBL27892350 | 0.89 | POLB (0.61) | POLBPOLA1POLD1TK1BCHE | |
| SCHEMBL18855348 | 0.88 | POLB (0.68) | POLBPOLA1POLD1TK1BCHE | |
| SCHEMBL3031874 | 0.88 | POLB (0.68) | POLBPOLA1POLD1TK1BCHE | |
| SCHEMBL77582 | 0.88 | POLB (0.68) | POLBPOLA1POLD1TK1BCHE | |
| SCHEMBL30586988 | 0.88 | POLB (0.68) | POLBPOLA1POLD1TK1BCHE | |
| Triphosphate SCHEMBL6138574 | 0.88 | POLB (0.58) | POLBPOLA1POLD1TK1BCHE | |
| SCHEMBL265387 | 0.88 | POLB (0.68) | POLBPOLA1POLD1TK1BCHE | |
| Triphosphate SCHEMBL6066341 | 0.86 | POLB (0.58) | POLBPOLA1POLD1TK1LMNA | |
| SCHEMBL28961478 | 0.86 | POLB (0.61) | POLBPOLA1POLD1TK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190203240-A1 | METHODS FOR THE PRODUCTION OF RHAMNOSYLATED FLAVONOIDS | UNIV HAMBURG (DE) | 2019-07-04 | — | — | US | disclosed |
| US-20190100549-A1 | FLAVONOIDE-TYPE COMPOUNDS BEARING AN O-RHAMNOSYL RESIDUE | UNIVERSITAET HAMBURG (DE) | 2019-04-04 | — | — | US | disclosed |
| EP-3402788-A1 | FLAVONOIDE-TYPE COMPOUNDS BEARING AN O-RHAMNOSYL RESIDUE | Universität Hamburg (DE) | 2018-11-21 | — | — | EP | disclosed |
| EP-3402893-A1 | METHODS FOR THE PRODUCTION OF RHAMNOSYLATED FLAVONOIDS | Universität Hamburg (DE) | 2018-11-21 | — | — | EP | disclosed |
| WO-2017121863-A1 | METHODS FOR THE PRODUCTION OF RHAMNOSYLATED FLAVONOIDS | UNIVERSITÄT HAMBURG (DE) | 2017-07-20 | — | — | WO | disclosed |
| WO-2017121855-A1 | FLAVONOIDE-TYPE COMPOUNDS BEARING AN O-RHAMNOSYL RESIDUE | UNIVERSITÄT HAMBURG (DE) | 2017-07-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190100549-A1 | FLAVONOIDE-TYPE COMPOUNDS BEARING AN O-RHAMNOSYL RESIDUE | LRAT, TYR, CUTA | POLB 2038/4885POLA1 2477/4885POLD1 2532/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.