Triphosphate

Triphosphate

SCHEMBL6066341

Cc1cn([C@H]2CC[C@@H](CO)O2)c(=O)[nH]c1=O.O=P(O)(O)OP(=O)(O)OP(=O)(O)O

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.58
POLA1 P09884 1/20 0.58
POLD1 P28340 1/20 0.58
TK1 P04183 5/20 0.58
LMNA P02545 2/20 0.53
TSHR P16473 2/20 0.53
ALB P02768 1/20 0.53
PKM P14618 1/20 0.53
BLM P54132 1/20 0.53
PMP22 Q01453 1/20 0.53
CYP2D6 P10635 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pyrophosphoric Acid SCHEMBL17541888 0.96 TK1 (0.60) POLBPOLA1POLD1TK1LMNA
Pyrophosphoric Acid SCHEMBL27805609 0.96 TK1 (0.60) POLBPOLA1POLD1TK1LMNA
SCHEMBL28961478 0.93 POLB (0.61) POLBPOLA1POLD1TK1LMNA
Phosphoric Acid SCHEMBL5709986 0.91 TK1 (0.58) POLBTK1LMNATSHRALB
Phosphoric Acid SCHEMBL18249308 0.91 TK1 (0.58) POLBTK1LMNATSHRALB
Phosphoric Acid SCHEMBL5147665 0.91 TK1 (0.58) POLBTK1LMNATSHRALB
Phosphoric Acid SCHEMBL7977953 0.91 TK1 (0.58) POLBTK1LMNATSHRALB
Triphosphate SCHEMBL27892350 0.89 POLB (0.61) POLBPOLA1POLD1TK1
SCHEMBL709680 0.89 POLB (0.57) POLBPOLA1POLD1TK1LMNA
SCHEMBL762579 0.89 LMNA (0.58) POLBTK1LMNATSHRALB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101878312-A Polymerase-based single-molecule sequencing ISIS INNOVATION 2010-11-03 CN claimed
CN-101724715-A Detection method of scylla serrata reoviruses UNIV HUAZHONG NORMAL 2010-06-09 CN claimed
CN-100519758-C Helicase-dependent amplification of nucleic acids NEW ENGLAND BIOLABS INC (US) 2009-07-29 CN claimed
CN-1688709-A Helicase dependent amplification of nucleic acids NEW ENGLAND BIOLABS INC (US) 2005-10-26 CN claimed
CN-1120887-C Process for preparing bio-degradable plastics by construction of genetically engineered cytoalgae UNIV TSINGHUA (CN) 2003-09-10 CN claimed
CN-1309183-A Process for preparing bio-degradable plastics by construction of genetically engineered cytoalgae UNIV QINGHUA (CN) 2001-08-22 CN claimed
CN-110446783-A Method for replication or amplification of circular DNA JAPAN SCIENCE & TECH AGENCY 2019-11-12 CN disclosed
CN-109415718-A Amplification method of circular DNA 国立研究开发法人科学技术振兴机构 2019-03-01 CN disclosed
CN-108398478-A Based on adenine/Au(Ⅲ)The construction method of the multi-functional electrochemical sensor of compound and application 宁波大学 2018-08-14 CN disclosed
CN-107922969-A The biology sensor of the cascade reaction of structure switching, digestion of nucleic acids and amplification comprising nucleic acid assembly 麦克马斯特大学 2018-04-17 CN disclosed
EP-2792745-B1 MODIFICATION OF HELPER T CELL-INDUCING POLYPEPTIDE NAT UNIV CORP KOCHI UNIV (JP) 2017-11-15 EP disclosed
CN-106715718-A Compositions and methods for detecting and analyzing Mycobacterium tuberculosis 雅培分子公司 2017-05-24 CN disclosed
CN-105985946-A Method for stabilizing thermal convection polymerase chain reaction flow field and thermal convection polymerase chain reaction device thereof 瑞基海洋生物科技股份有限公司 2016-10-05 CN disclosed
CN-1034134-A Be used for the treatment of compositions and preparation method that back virus merges cancer UNIV LIVERPOOL (GB) 1989-07-26 CN disclosed
CN-1030093-A The production of peptide TAKEDA CHEMICAL INDUSTRIES LTD (JP) 1989-01-04 CN disclosed
CN-87108308-A New polypeptide and production thereof 1988-08-17 CN disclosed
CN-87105787-A The thermostability enzyme of purifying and with its increase, the method for detection and/or cloning nucleic acid sequences 1988-05-11 CN disclosed
CN-85109606-A REVERSE SPOT MOLECULAR HYBRIDIZATION TECHNIQUE 1987-06-17 CN disclosed
CN-85103306-A The purification of recombinant interleukin element-2 1987-05-27 CN disclosed
CN-86106260-A Novel protein and process for producing the same 1987-04-08 CN disclosed