SCHEMBL19132154

SCHEMBL19132154

c1ccc(-n2c3ccc(-c4ccc5c(c4)c4ccc6ccccc6c4n5-c4ccccc4)cc3c3cc4c5ccccc5c5ccccc5c4cc32)cc1

nearest known ligand 0.40

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.40
ATM Q13315 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
CYP1A2 P05177 1/20 0.35
CYP2C9 P11712 1/20 0.35
CYP2C19 P33261 1/20 0.35
HPRT1 P00492 4/20 0.33
PTGER4 P35408 1/20 0.32
MAPK1 P28482 1/20 0.32
MAT2A P31153 1/20 0.30
KMT2A Q03164 1/20 0.30
FDPS P14324 1/20 0.30
IL1R1 P14778 1/20 0.30
SIRT2 Q8IXJ6 1/20 0.30
SIRT1 Q96EB6 1/20 0.30
TDP1 Q9NUW8 1/20 0.30
ALDH1A1 P00352 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19132481 0.97 KDM4E (0.41) KDM4EATML3MBTL1CYP1A2CYP2C9
SCHEMBL19132476 0.92 HPRT1 (0.41) KDM4EATML3MBTL1CYP1A2CYP2C9
SCHEMBL21035263 0.91 KDM4E (0.38) KDM4EATML3MBTL1CYP1A2CYP2C9
SCHEMBL19131725 0.91 L3MBTL1 (0.41) KDM4EATML3MBTL1HPRT1PTGER4
SCHEMBL17298652 0.91 L3MBTL1 (0.51) KDM4EATML3MBTL1HPRT1PTGER4
SCHEMBL19131248 0.89 L3MBTL1 (0.50) KDM4EATML3MBTL1CYP1A2CYP2C9
SCHEMBL16405417 0.89 L3MBTL1 (0.44) KDM4EATML3MBTL1CYP1A2CYP2C9
SCHEMBL16405418 0.89 L3MBTL1 (0.44) KDM4EATML3MBTL1CYP1A2CYP2C9
SCHEMBL24765797 0.87 L3MBTL1 (0.47) KDM4EATML3MBTL1PTGER4KMT2A
SCHEMBL24627338 0.87 L3MBTL1 (0.47) KDM4EATML3MBTL1PTGER4KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11075343-B2 Organic light emitting compounds and organic light emitting devices including the same SFC CO., LTD. (KR) 2021-07-27 US disclosed
US-20170207397-A1 ORGANIC LIGHT EMITTING COMPOUNDS AND ORGANIC LIGHT EMITTING DEVICES INCLUDING THE SAME SFC CO., LTD. (KR) 2017-07-20 US disclosed
US-20170207397-A1 ORGANIC LIGHT EMITTING COMPOUNDS AND ORGANIC LIGHT EMITTING DEVICES INCLUDING THE SAME SFC CO., LTD. (KR) 2017-07-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11075343-B2 Organic light emitting compounds and organic light emitting devices including the same HARS1, ALDH1A2, NR2E3 KDM4E 3813/4885ATM 4125/4885L3MBTL1 562/4885
US-20170207397-A1 ORGANIC LIGHT EMITTING COMPOUNDS AND ORGANIC LIGHT EMITTING DEVICES INCLUDING THE SAME HARS1, ALDH1A2, ALDH1A3 KDM4E 3906/4885ATM 4456/4885L3MBTL1 451/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.