SCHEMBL19132166

SCHEMBL19132166

c1ccc(-n2c3ccc(-c4cccc5c4sc4ccccc45)cc3c3ccc4c5ccccc5ccc4c32)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.46
PRKDC P78527 5/20 0.39
S1PR4 O95977 5/20 0.34
S1PR5 Q9H228 5/20 0.34
PARP14 Q460N5 1/20 0.32
CYP1A1 P04798 2/20 0.32
CYP1B1 Q16678 2/20 0.32
F9 P00740 1/20 0.32
MAPT P10636 2/20 0.31
RXFP1 Q9HBX9 1/20 0.31
PIK3CD O00329 2/20 0.31
PIK3CB P42338 2/20 0.31
BRD4 O60885 1/20 0.31
PIK3CA P42336 1/20 0.31
MTOR P42345 1/20 0.31
PIK3CG P48736 1/20 0.31
KCNH2 Q12809 1/20 0.31
BRDT Q58F21 1/20 0.31
TLR4 O00206 1/20 0.30
CYP1A2 P05177 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20311911 0.91 ALOX5 (0.44) ALOX5PRKDCS1PR4S1PR5PARP14
SCHEMBL15126540 0.89 ALOX5 (0.43) ALOX5PRKDCS1PR4S1PR5PARP14
SCHEMBL26704752 0.89 ALOX5 (0.50) ALOX5PRKDCPARP14F9MAPT
SCHEMBL10165709 0.88 ALOX5 (0.51) ALOX5PRKDCS1PR4S1PR5PARP14
SCHEMBL18505188 0.87 ALOX5 (0.41) ALOX5PRKDCS1PR4S1PR5PARP14
SCHEMBL457689 0.86 ALOX5 (0.57) ALOX5PRKDCPARP14F9MAPT
SCHEMBL18505080 0.86 ALOX5 (0.41) ALOX5PRKDCS1PR4S1PR5PARP14
SCHEMBL18505079 0.86 ALOX5 (0.41) ALOX5PRKDCS1PR4S1PR5PARP14
SCHEMBL23783796 0.86 ALOX5 (0.49) ALOX5PRKDCPARP14MAPTRXFP1
SCHEMBL780711 0.86 ALOX5 (0.49) ALOX5PRKDCS1PR4S1PR5PARP14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11075343-B2 Organic light emitting compounds and organic light emitting devices including the same SFC CO., LTD. (KR) 2021-07-27 US disclosed
US-20170207397-A1 ORGANIC LIGHT EMITTING COMPOUNDS AND ORGANIC LIGHT EMITTING DEVICES INCLUDING THE SAME SFC CO., LTD. (KR) 2017-07-20 US disclosed
US-20170207397-A1 ORGANIC LIGHT EMITTING COMPOUNDS AND ORGANIC LIGHT EMITTING DEVICES INCLUDING THE SAME SFC CO., LTD. (KR) 2017-07-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11075343-B2 Organic light emitting compounds and organic light emitting devices including the same HARS1, ALDH1A2, NR2E3 ALOX5 1194/4885PRKDC 4712/4885S1PR4 4381/4885
US-20170207397-A1 ORGANIC LIGHT EMITTING COMPOUNDS AND ORGANIC LIGHT EMITTING DEVICES INCLUDING THE SAME HARS1, ALDH1A2, ALDH1A3 ALOX5 1196/4885PRKDC 4611/4885S1PR4 4023/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.