Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 1/20 | 0.44 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.44 |
| ▸ | FFAR3 | O14843 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | KDM6B | O15054 | 1/20 | 0.35 |
| ▸ | KDM5C | P41229 | 1/20 | 0.35 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.35 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.35 |
| ▸ | CTH | P32929 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | FNTA | P49354 | 1/20 | 0.33 |
| ▸ | FNTB | P49356 | 1/20 | 0.33 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.33 |
| ▸ | FYN | P06241 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL102551 | 1.00 | LDHA (0.44) | LDHASRRFFAR3LMNASLC15A2 | |
| SCHEMBL102549 | 1.00 | LDHA (0.44) | LDHASRRFFAR3LMNASLC15A2 | |
| Malonic Acid SCHEMBL3867313 | 0.81 | LDHA (0.45) | LDHASRRFFAR3LMNASLC15A2 | |
| SCHEMBL6647501 | 0.81 | LDHA (0.57) | LDHASRRFFAR3LMNASLC15A2 | |
| SCHEMBL6647502 | 0.81 | LDHA (0.57) | LDHASRRFFAR3LMNASLC15A2 | |
| SCHEMBL7709330 | 0.77 | LDHA (0.44) | LDHASRRFFAR3LMNASLC15A2 | |
| SCHEMBL11348969 | 0.76 | THRB (0.30) | THRBFNTAFNTBPGGT1B | |
| SCHEMBL11348965 | 0.76 | THRB (0.30) | THRBFNTAFNTBPGGT1B | |
| SCHEMBL3614641 | 0.75 | — | — | |
| SCHEMBL811388 | 0.74 | LMNA (0.52) | FFAR3LMNASLC15A2KDM4EEGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9708331-B2 | Metabotrophic glutamate receptor 5 modulators and methods of use thereof | SUNOVION PHARMACEUTICALS INC. (US) | 2017-07-18 | — | — | US | disclosed |