SCHEMBL19137403

SCHEMBL19137403

C=Cc1ccc(C(O)c2ccccc2)cc1

nearest known ligand 0.56

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.56
TSHR P16473 2/20 0.56
SMN1; SMN2 Q16637 1/20 0.45
CA12 O43570 1/20 0.43
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
CA9 Q16790 1/20 0.43
CA14 Q9ULX7 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.42
SRD5A2 P31213 1/20 0.39
HSD17B2 P37059 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
CYP2C19 P33261 1/20 0.38
LMNA P02545 3/20 0.38
MAPK1 P28482 1/20 0.38
LTA4H P09960 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7524035 0.84 ALDH1A1 (0.59) ALDH1A1TSHRHSD17B2TDP1CYP2C19
SCHEMBL8671295 0.83 SMN1; SMN2 (0.58) TSHRSMN1; SMN2CA12CA1CA2
SCHEMBL9806285 0.80 ALDH1A1 (0.54) ALDH1A1TSHRCYP2C19LMNA
SCHEMBL1903577 0.80 ALDH1A1 (0.54) ALDH1A1TSHRHSD17B2TDP1CYP2C19
SCHEMBL6124173 0.80 ALDH1A1 (0.54) ALDH1A1SMN1; SMN2CA12CA1CA2
Diphenylmethanol SCHEMBL6434457 0.80 SMN1; SMN2 (0.61) TSHRSMN1; SMN2CA12CA1CA2
Diphenylmethanol SCHEMBL41571 0.80 SMN1; SMN2 (0.61) TSHRSMN1; SMN2CA12CA1CA2
Diphenylmethanol SCHEMBL11564700 0.80 SMN1; SMN2 (0.61) TSHRSMN1; SMN2CA12CA1CA2
Diphenylmethanol SCHEMBL10868602 0.80 SMN1; SMN2 (0.61) TSHRSMN1; SMN2CA12CA1CA2
Aminodiphenylmethane SCHEMBL9499747 0.77 ALDH1A1 (0.56) ALDH1A1TSHRLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021093556-A1 METHOD FOR PREPARING HYDROXYL COMPOUND, DEUTERATED COMPOUND THEREOF, AND TRITIATED COMPOUND THEREOF 中国科学院福建物质结构研究所 2021-05-20 WO disclosed
EP-3203319-B1 POLYMER COMPOUND, NEGATIVE RESIST COMPOSITION, LAMINATE, PATTERNING PROCESS, AND COMPOUND SHINETSU CHEMICAL CO (JP) 2018-06-20 EP disclosed
US-9969829-B2 Polymer compound, negative resist composition, laminate, patterning process, and compound SHIN-ETSU CHEMICAL CO., LTD. (JP) 2018-05-15 US disclosed
CN-107037690-A High-molecular compound, negative resist composition, layered product, pattern formation method and compound 信越化学工业株式会社 2017-08-11 CN disclosed
EP-3203319-A1 POLYMER COMPOUND, NEGATIVE RESIST COMPOSITION, LAMINATE, PATTERNING PROCESS, AND COMPOUND Shin-Etsu Chemical Co., Ltd. (JP) 2017-08-09 EP disclosed
US-20170210836-A1 POLYMER COMPOUND, NEGATIVE RESIST COMPOSITION, LAMINATE, PATTERNING PROCESS, AND COMPOUND SHIN-ETSU CHEMICAL CO., LTD. (JP) 2017-07-27 US disclosed
US-20160376255-A1 QUINOLONE INHIBITORS OF LIPOPROTEIN-ASSOCIATED PHOSPHOLIPASE A2 AUSPEX PHARMACEUTICALS INC (US) 2016-12-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160376255-A1 QUINOLONE INHIBITORS OF LIPOPROTEIN-ASSOCIATED PHOSPHOLIPASE A2 PLA2G4A, PLA2G12A, PLA2G4B ALDH1A1 2665/4885TSHR 4388/4885SMN1; SMN2 4774/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.