Aminodiphenylmethane

Aminodiphenylmethane

SCHEMBL9499747

C=Cc1ccc(C=C)cc1.NC(c1ccccc1)c1ccccc1

nearest known ligand 0.64

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Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.56
TSHR P16473 1/20 0.56
DPP4 P27487 2/20 0.44
F2 P00734 1/20 0.44
ADRA2A P08913 1/20 0.40
ADRA2C P18825 1/20 0.40
LMNA P02545 1/20 0.40
HIF1A Q16665 1/20 0.40
KDM4E B2RXH2 1/20 0.40
HTR2A P28223 1/20 0.36
TAAR1 Q96RJ0 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Aminodiphenylmethane SCHEMBL4340486 0.95 ALDH1A1 (0.64) ALDH1A1TSHRDPP4F2ADRA2A
Hydrochloric Acid SCHEMBL5493381 0.87 ALDH1A1 (0.43) ALDH1A1TSHRDPP4F2ADRA2A
Styrene SCHEMBL7656757 0.83 ALDH1A1 (0.48) ALDH1A1TSHRDPP4F2ADRA2A
Aminodiphenylmethane SCHEMBL7897875 0.82 ALDH1A1 (0.48) ALDH1A1TSHRDPP4F2ADRA2A
Aminodiphenylmethane SCHEMBL11059631 0.81 DPP4 (0.48) ALDH1A1DPP4F2ADRA2AADRA2C
Aminodiphenylmethane SCHEMBL7841 0.80 DPP4 (0.65) TSHRDPP4F2ADRA2AADRA2C
SCHEMBL7524035 0.79 ALDH1A1 (0.59) ALDH1A1TSHRDPP4F2LMNA
SCHEMBL19137403 0.77 ALDH1A1 (0.56) ALDH1A1TSHRLMNA
Aminodiphenylmethane SCHEMBL1764753 0.77 DPP4 (0.61) ALDH1A1DPP4F2ADRA2AADRA2C
Aminodiphenylmethane SCHEMBL8686295 0.77 DPP4 (0.61) TSHRDPP4F2ADRA2AADRA2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0138416-B1 GROWTH HORMONE RELEASE FACTOR ANALOGS ELI LILLY AND COMPANY (US) 1993-04-28 EP disclosed
US-4617149-A ANIMAL GROWTH REGULATORS ELI LILLY AND COMPANY (US) 1986-10-14 US disclosed
EP-0138416-A2 Growth hormone release factor analogs ELI LILLY AND COMPANY (US) 1985-04-24 EP disclosed