Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX1 | P51575 | 9/20 | 0.64 |
| ▸ | KCNMA1 | Q12791 | 5/20 | 0.64 |
| ▸ | TMPRSS4 | Q9NRS4 | 6/20 | 0.62 |
| ▸ | P2RX4 | Q99571 | 5/20 | 0.62 |
| ▸ | P2RX7 | Q99572 | 5/20 | 0.62 |
| ▸ | CA1 | P00915 | 1/20 | 0.60 |
| ▸ | CA2 | P00918 | 1/20 | 0.60 |
| ▸ | CDK1 | P06493 | 1/20 | 0.57 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.53 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.53 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | IKBKB | O14920 | 1/20 | 0.53 |
| ▸ | CHUK | O15111 | 1/20 | 0.53 |
| ▸ | KDR | P35968 | 1/20 | 0.53 |
| ▸ | FLT3 | P36888 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | MYLK | Q15746 | 1/20 | 0.53 |
| ▸ | MAP4K5 | Q9Y4K4 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11324189 | 0.84 | P2RX1 (0.68) | P2RX1KCNMA1TMPRSS4P2RX4P2RX7 | |
| SCHEMBL5506621 | 0.82 | P2RX1 (0.66) | P2RX1KCNMA1TMPRSS4P2RX4P2RX7 | |
| SCHEMBL3871841 | 0.81 | P2RX1 (0.64) | P2RX1KCNMA1TMPRSS4P2RX4P2RX7 | |
| SCHEMBL3277584 | 0.81 | ALDH1A1 (0.70) | P2RX1KCNMA1TMPRSS4P2RX4P2RX7 | |
| SCHEMBL2169619 | 0.78 | P2RX1 (1.00) | P2RX1KCNMA1TMPRSS4P2RX4P2RX7 | |
| SCHEMBL29454776 | 0.78 | P2RX1 (1.00) | P2RX1KCNMA1TMPRSS4P2RX4P2RX7 | |
| SCHEMBL6401690 | 0.78 | CA1 (0.67) | P2RX1KCNMA1TMPRSS4P2RX4P2RX7 | |
| SCHEMBL6966672 | 0.77 | CA1 (0.72) | P2RX1KCNMA1TMPRSS4P2RX4P2RX7 | |
| SCHEMBL21423064 | 0.77 | ALOX5 (0.66) | P2RX1KCNMA1TMPRSS4P2RX4P2RX7 | |
| SCHEMBL27786747 | 0.77 | TMPRSS4 (0.60) | P2RX1KCNMA1TMPRSS4P2RX4P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3192794-A1 | SUSTAINED HIV PROTEASE INHIBITOR | Shionogi & Co., Ltd. (JP) | 2017-07-19 | — | — | EP | disclosed |