Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMD14 | O00487 | 2/20 | 0.42 |
| ▸ | PLA2G1B | P04054 | 2/20 | 0.42 |
| ▸ | MMP2 | P08253 | 2/20 | 0.42 |
| ▸ | ATG4B | Q9Y4P1 | 2/20 | 0.42 |
| ▸ | RAD52 | P43351 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | DNM1 | Q05193 | 4/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.38 |
| ▸ | FDPS | P14324 | 3/20 | 0.38 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.36 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4895294 | 1.00 | PSMD14 (0.42) | PSMD14PLA2G1BMMP2ATG4BRAD52 | |
| Hydrochloric Acid SCHEMBL4889265 | 1.00 | PSMD14 (0.42) | PSMD14PLA2G1BMMP2ATG4BRAD52 | |
| Hydrochloric Acid SCHEMBL4891156 | 1.00 | PSMD14 (0.42) | PSMD14PLA2G1BMMP2ATG4BRAD52 | |
| Hydrochloric Acid SCHEMBL9719666 | 1.00 | PSMD14 (0.42) | PSMD14PLA2G1BMMP2ATG4BRAD52 | |
| SCHEMBL8139870 | 0.98 | LMNA (0.43) | PSMD14PLA2G1BMMP2ATG4BRAD52 | |
| SCHEMBL8152563 | 0.98 | LMNA (0.43) | PSMD14PLA2G1BMMP2ATG4BRAD52 | |
| Hydrochloric Acid SCHEMBL19436589 | 0.91 | PSMD14 (0.42) | PSMD14PLA2G1BMMP2ATG4BRAD52 | |
| Hydrochloric Acid SCHEMBL1298197 | 0.91 | LMNA (0.44) | PSMD14PLA2G1BMMP2ATG4BRAD52 | |
| Hydrochloric Acid SCHEMBL9575883 | 0.87 | PSMD14 (0.42) | PSMD14PLA2G1BMMP2ATG4BRAD52 | |
| Hydrochloric Acid SCHEMBL1914719 | 0.84 | TSHR (0.38) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080020217-A1 | Colorless Transparent Polyimide Composite Film and Method for Producing Same | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2008-01-24 | — | — | US | disclosed |