Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNJ1 | P48048 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ALDH1A3 | P47895 | 5/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.34 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.34 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11400903 | 0.84 | ALDH1A1 (0.43) | KCNJ1ALDH1A1MEN1GAAMAPT | |
| SCHEMBL20455902 | 0.78 | KCNJ1 (0.51) | KCNJ1ALDH1A1MEN1GAAMAPT | |
| SCHEMBL3800178 | 0.76 | KMT2A (0.42) | ALDH1A1MAPTHPGDKMT2ASMN1; SMN2 | |
| SCHEMBL6937611 | 0.72 | MAPT (0.48) | KCNJ1ALDH1A1MEN1MAPTHPGD | |
| SCHEMBL86299 | 0.70 | MAOA (0.50) | ALDH1A1MAPTKMT2AALDH3A1TDP1 | |
| SCHEMBL27566504 | 0.69 | SMN1; SMN2 (0.36) | ALDH1A1MAPTHPGDKMT2ASMN1; SMN2 | |
| SCHEMBL86309 | 0.69 | S100A4 (0.44) | ALDH1A1MAPTKMT2ASMN1; SMN2ALDH3A1 | |
| SCHEMBL24180108 | 0.68 | SMN1; SMN2 (0.41) | ALDH1A1MAPTHPGDKMT2ASMN1; SMN2 | |
| Ethylene SCHEMBL7815591 | 0.68 | MAOA (0.47) | ALDH1A1MAPTKMT2AALDH3A1TDP1 | |
| SCHEMBL21873388 | 0.68 | ALDH1A1 (0.47) | KCNJ1ALDH1A1MEN1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017123884-A1 | HETEROCYCLIC COMPOUNDS AS RSV INHIBITORS | ENANTA PHARMACEUTICALS, INC. (US) | 2017-07-20 | — | — | WO | disclosed |