3-Chloro-1-Methyl-1H-Pyrazole-5-Carboxylic Acid

3-Chloro-1-Methyl-1H-Pyrazole-5-Carboxylic Acid

SCHEMBL1915166

Cn1nc(Cl)cc1C(=O)O

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRN P28799 3/20 0.56
SORT1 Q99523 3/20 0.56
KDM4E B2RXH2 2/20 0.56
PKM P14618 1/20 0.40
HCAR3 P49019 1/20 0.40
CA12 O43570 1/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
CA9 Q16790 1/20 0.38
ALDH1A1 P00352 2/20 0.37
MAPK1 P28482 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
TPMT P51580 1/20 0.37
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
HCAR2 Q8TDS4 1/20 0.35
PTPN1 P18031 1/20 0.35
NAPRT Q6XQN6 1/20 0.35
GPR35 Q9HC97 1/20 0.35
MCL1 Q07820 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
3-Chloro-1-Methyl-1H-Pyrazole-5-Carboxylic Acid SCHEMBL27453073 0.84 KDM4E (0.43) GRNSORT1KDM4EPKMHCAR3
SCHEMBL3058674 0.83 KDM4E (0.39) GRNSORT1KDM4EPKMALDH1A1
SCHEMBL1915343 0.79 CA12 (0.42) KDM4EPKMCA12CA1CA2
SCHEMBL8124795 0.77 KDM4E (0.47) KDM4EALDH1A1MEN1KMT2AGAA
SCHEMBL15059353 0.77 GRN (0.58) GRNSORT1KDM4EPKMHCAR3
SCHEMBL70171 0.77 KDM4E (0.58) GRNSORT1KDM4EPKMHCAR3
SCHEMBL286931 0.77 KDM4E (0.58) GRNSORT1KDM4EPKMHCAR3
SCHEMBL16949533 0.76 KDM4E (0.53) GRNSORT1KDM4EPKMHCAR3
Hydrochloric Acid SCHEMBL9680540 0.75 KDM4E (0.56) GRNSORT1KDM4EPKMHCAR3
SCHEMBL1663229 0.75 GRN (0.56) GRNSORT1KDM4EPKMHCAR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250160275-A1 COMPOUNDS FOR MODIFYING MEIOTIC RECOMBINATION AND METHODS RELATING THERETO THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL 2025-05-22 US claimed
WO-2023164606-A1 COMPOUNDS FOR MODIFYING MEIOTIC RECOMBINATION AND METHODS RELATING THERETO THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 2023-08-31 WO claimed
US-20220022454-A1 SYNERGISTIC MIXTURE OF PLANT DEFENSE INDUCTORS LIDA PLANT RESEARCH S.L. (ES) 2022-01-27 US claimed
EP-3915368-A1 SYNERGISTIC MIXTURE OF PLANT DEFENSE INDUCTORS LIDA Plant Research S.L. (ES) 2021-12-01 EP claimed
CN-112512322-A Synergistic mixtures of plant defense inducers 利达植物研究有限公司 2021-03-16 CN claimed
EP-3780957-A1 SYNERGISTIC MIXTURE OF PLANT DEFENSE INDUCTORS LIDA Plant Research S.L. (ES) 2021-02-24 EP claimed
WO-2019202050-A1 SYNERGISTIC MIXTURE OF PLANT DEFENSE INDUCTORS LIDA PLANT RESEARCH S.L. (ES) 2019-10-24 WO claimed
US-12389905-B2 Synergistic mixture of plant defense inductors LIDA PLANT RESEARCH S.L. (ES) 2025-08-19 US disclosed
US-20250160275-A1 COMPOUNDS FOR MODIFYING MEIOTIC RECOMBINATION AND METHODS RELATING THERETO THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL 2025-05-22 US disclosed
EP-4551686-A1 METHOD FOR ISOLATING PLANT STEM CELLS FROM PLANT LEAVES AND THE ASSOCIATED CELL LINES OBTAINED UTILISING THE METHOD Green Bioactives Limited (GB) 2025-05-14 EP disclosed
CN-119836470-A Method for isolating plant stem cells from leaves of plants and related cell lines obtained by the method 绿源生物活性有限公司 2025-04-15 CN disclosed
EP-4405334-B1 SORTILIN INHIBITORS SORTINA PHARMA AB (SE) 2025-02-12 EP disclosed
US-20250002460-A1 SORTILIN INHIBITORS SORTINA PHARMA AB (SE) 2025-01-02 US disclosed
EP-2049541-A2 FUSED HETEROCYCLIC DERIVATIVE AND USE THEREOF Takeda Pharmaceutical Company Limited (JP) 2009-04-22 EP disclosed
WO-2008016192-A2 FUSED HETEROCYCLIC DERIVATIVE AND USE THEREOF TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2008-02-07 WO disclosed
CN-1058490-C Tetrazolinone derivatives BAYER AGROCHEM KK (JP) 2000-11-15 CN disclosed
EP-0757987-B1 Pyrazole-carboxylic acid derivatives as plant disease control agents NISSAN CHEMICAL IND LTD (JP) 2000-07-19 EP disclosed
US-5817829-A FUNGICIDES NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 1998-10-06 US disclosed
CN-1146764-A Pyrazolecarboxylic acid derivative and plant disease control agent NISSAN CHEMICAL IND LTD (JP) 1997-04-02 CN disclosed
EP-0757987-A1 PYRAZOLECARBOXYLIC ACID DERIVATIVE AND PLANT DISEASE CONTROL AGENT NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) 1997-02-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220022454-A1 SYNERGISTIC MIXTURE OF PLANT DEFENSE INDUCTORS STING1, MYD88, RIPK1 GRN 2906/4885SORT1 2686/4885KDM4E 3300/4885
US-12389905-B2 Synergistic mixture of plant defense inductors STING1, MYD88, RIPK1 GRN 2906/4885SORT1 2686/4885KDM4E 3300/4885
US-20250002460-A1 SORTILIN INHIBITORS SORT1, GRN, SCARB1 GRN 2/4885SORT1 1/4885KDM4E 4845/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.