Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 2/20 | 0.34 |
| ▸ | TTR | P02766 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.33 |
| ▸ | CYP26A1 | O43174 | 4/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2030406 | 0.73 | POLB (0.38) | POLBL3MBTL1HTTAPEX1TTR | |
| SCHEMBL7958414 | 0.71 | PTGER4 (0.47) | POLBL3MBTL1APEX1TTRNPC1 | |
| SCHEMBL2398239 | 0.69 | MIF (0.45) | POLBL3MBTL1APEX1NPC1GAA | |
| SCHEMBL1916048 | 0.68 | KMT2A (0.49) | — | |
| SCHEMBL7960304 | 0.66 | APEX1 (0.38) | POLBL3MBTL1APEX1TTRNPC1 | |
| SCHEMBL27679696 | 0.65 | SLC22A6 (0.45) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL1915970 | 0.65 | CPA3 (0.56) | — | |
| SCHEMBL20543848 | 0.65 | L3MBTL1 (0.42) | POLBL3MBTL1HTTTAS1R3TAS1R1 | |
| SCHEMBL1915040 | 0.63 | KMT2A (0.41) | POLBL3MBTL1HTT | |
| SCHEMBL1915691 | 0.63 | SMN1; SMN2 (0.40) | POLBHTTNPC1GAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011076734-A1 | COMPOUNDS, PHARMACEUTICAL COMPOSITION AND METHODS FOR USE IN TREATING INFLAMMATORY DISEASES | EUROSCREEN S.A. (BE) | 2011-06-30 | — | — | WO | disclosed |