Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17439466 | 0.79 | SMN1; SMN2 (0.41) | MEN1KMT2APKMHIF1ASMN1; SMN2 | |
| SCHEMBL28639887 | 0.77 | ALDH1A1 (0.41) | MEN1KMT2AALDH1A1ADORA2ACNR1 | |
| SCHEMBL19615579 | 0.75 | PKM (0.36) | MEN1KMT2APKMHTTHIF1A | |
| SCHEMBL30826356 | 0.74 | ADORA2A (0.39) | MEN1KMT2APKMHTTHIF1A | |
| SCHEMBL17439469 | 0.73 | KMT2A (0.46) | MEN1KMT2AALOX5TSHR | |
| SCHEMBL31026178 | 0.73 | ALOX5 (0.39) | MEN1KMT2APKMHTTHIF1A | |
| SCHEMBL12243140 | 0.72 | FBP1 (0.38) | MEN1KMT2APKMHTTHIF1A | |
| SCHEMBL22863282 | 0.72 | FBP1 (0.38) | MEN1KMT2APKMHTTHIF1A | |
| SCHEMBL21791636 | 0.72 | MEN1 (0.40) | MEN1KMT2APKMHTTHIF1A | |
| SCHEMBL27815006 | 0.72 | ALDH1A1 (0.42) | MEN1KMT2AHTTALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011076744-A1 | DISUBSTITUTED HETEROARYL-FUSED PYRIDINES | NOVARTIS AG (CH) | 2011-06-30 | — | — | WO | disclosed |