Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 3/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.35 |
| ▸ | TDO2 | P48775 | 1/20 | 0.33 |
| ▸ | PNP | P00491 | 1/20 | 0.33 |
| ▸ | IL5 | P05113 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | PRNP | P04156 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7657497 | 0.85 | UHRF1 (0.35) | MAPTUHRF1PARP1CHEK1PIM1 | |
| SCHEMBL29872244 | 0.78 | KDM4E (0.35) | MAPTPARP1CHEK1PIM1RPS6KA3 | |
| SCHEMBL18237575 | 0.77 | KDM5B (0.33) | PNP | |
| SCHEMBL29872631 | 0.77 | MAPT (0.41) | MAPTPARP1TDO2 | |
| SCHEMBL22962863 | 0.77 | PARP1 (0.41) | MAPTPARP1CHEK1PIM1RPS6KA3 | |
| SCHEMBL29638516 | 0.74 | PARP1 (0.54) | PARP1CHEK1PIM1RPS6KA3MEN1 | |
| SCHEMBL13003705 | 0.74 | PARP1 (0.54) | PARP1CHEK1PIM1RPS6KA3MEN1 | |
| SCHEMBL25375705 | 0.73 | PARP1 (0.38) | MAPTPARP1CHEK1PIM1RPS6KA3 | |
| SCHEMBL30402730 | 0.73 | PARP1 (0.38) | MAPTPARP1CHEK1PIM1RPS6KA3 | |
| SCHEMBL19153714 | 0.73 | ALDH1A1 (0.49) | MAPTTDO2IL5KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170202970-A1 | SILICON BASED DRUG CONJUGATES AND METHODS OF USING SAME | BLINKBIO, INC. | 2017-07-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170202970-A1 | SILICON BASED DRUG CONJUGATES AND METHODS OF USING SAME | CD44, MSN, AS3MT | MAPT 1162/4885UHRF1 2152/4885PARP1 2195/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.