SCHEMBL13003705

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL29638516	1.00	PARP1 (0.54)	PARP1CHEK1PIM1RPS6KA3NR4A2
	SCHEMBL1507612	0.85	PARP1 (0.54)	PARP1CHEK1PIM1RPS6KA3NR4A2
	SCHEMBL12489082	0.79	PIM1 (0.51)	CHEK1PIM1RPS6KA3SMN1; SMN2IDO1
	SCHEMBL2191216	0.78	ALDH1A1 (0.55)	PARP1PIM1NR4A2RXFP1SMN1; SMN2
	SCHEMBL29798728	0.78	PARP1 (0.50)	PARP1CHEK1IDO1HTR2A
	SCHEMBL1663769	0.78	PRKCI (0.56)	PARP1CHEK1PIM1RPS6KA3SMN1; SMN2
	SCHEMBL1663176	0.78	LMNA (0.51)	PARP1SMN1; SMN2HTR2AHTTMEN1
	SCHEMBL144025	0.78	PARP1 (0.50)	PARP1CHEK1PIM1RPS6KA3SMN1; SMN2
	SCHEMBL1345856	0.78	PARP1 (0.50)	PARP1CHEK1IDO1HTR2A
	SCHEMBL28572232	0.77	MMP12 (0.60)	RXFP1SMN1; SMN2HTR2AMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.