Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 5/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.44 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.44 |
| ▸ | USP2 | O75604 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.44 |
| ▸ | PDE2A | O00408 | 1/20 | 0.44 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.44 |
| ▸ | PDE5A | O76074 | 1/20 | 0.44 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4085302 | 0.84 | SMN1; SMN2 (0.52) | CA2LMNASMN1; SMN2ALDH1A1MAPK1 | |
| SCHEMBL19158877 | 0.76 | KDM4C (0.40) | KDM4EL3MBTL1 | |
| SCHEMBL19159106 | 0.74 | KDM4C (0.37) | — | |
| SCHEMBL17503761 | 0.74 | PDGFRB (0.44) | CA2SMN1; SMN2ALDH1A1MAPK1CYP3A4 | |
| SCHEMBL26711507 | 0.72 | KDM4C (0.43) | KDM4E | |
| SCHEMBL10997812 | 0.72 | DHFR (0.53) | CA2LMNASMN1; SMN2ALDH1A1MAPK1 | |
| SCHEMBL3924901 | 0.71 | CA2 (0.66) | CA2LMNASMN1; SMN2ALDH1A1MAPK1 | |
| SCHEMBL15819502 | 0.70 | NTSR1 (0.59) | ALDH1A1MAPK1PDE3BPDE3AKDM4E | |
| SCHEMBL17898316 | 0.70 | KDM4C (0.55) | — | |
| SCHEMBL16095498 | 0.70 | HASPIN (0.39) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970211-B1 | HISTONE DEMETHYLASE INHIBITORS | QUANTICEL PHARMACEUTICALS INC (US) | 2017-07-26 | — | — | EP | disclosed |