Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 13/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 9/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.40 |
| ▸ | ADORA2B | P29275 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | GSK3A | P49840 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | PTPN7 | P35236 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19160255 | 0.88 | ADORA2A (0.48) | ADORA2APOLBKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL1677411 | 0.82 | ADORA2A (0.48) | ADORA2APOLBKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL846080 | 0.82 | ALDH1A1 (0.49) | ADORA2APOLBKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL879421 | 0.80 | L3MBTL1 (0.47) | ADORA2APOLBKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL1254395 | 0.79 | ADORA2A (0.43) | ADORA2APOLBKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL17244105 | 0.78 | ADORA2A (0.43) | ADORA2APOLBKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL1255696 | 0.78 | ADORA2A (0.45) | ADORA2APOLBKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL1255819 | 0.78 | ADORA2A (0.60) | ADORA2APOLBKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL1255923 | 0.77 | L3MBTL1 (0.54) | ADORA2APOLBKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL1255858 | 0.77 | KDM4E (0.62) | ADORA2APOLBKDM4EALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1921077-B1 | AGENT FOR TREATING AND/OR PREVENTING SLEEP DISORDER | KYOWA HAKKO KIRIN CO LTD (JP) | 2017-07-26 | — | — | EP | disclosed |