Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 3/20 | 0.39 |
| ▸ | HTR2A | P28223 | 4/20 | 0.38 |
| ▸ | HTR2C | P28335 | 4/20 | 0.38 |
| ▸ | HTR2B | P41595 | 4/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.35 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6856816 | 0.91 | HRH3 (0.47) | ACHEHRH3MEN1ALDH1A1KMT2A | |
| SCHEMBL5404613 | 0.81 | ACHE (0.46) | ACHEHTR2AHTR2CHTR2BCYP1A2 | |
| SCHEMBL27288985 | 0.80 | ACHE (0.45) | ACHEHTR2AHTR2CHTR2BCYP1A2 | |
| SCHEMBL13214309 | 0.78 | XIAP (0.50) | ACHEMEN1ALDH1A1KMT2AKDM4E | |
| SCHEMBL93954 | 0.77 | ESR1 (0.54) | HTR2AHTR2CHTR2BCYP1A2CYP3A4 | |
| SCHEMBL18593246 | 0.76 | ACHE (0.49) | ACHEHRH3MEN1KMT2AMAPT | |
| SCHEMBL20195796 | 0.76 | KMT2A (0.52) | CYP1A2CYP2D6HRH3MEN1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL11030093 | 0.76 | ESR1 (0.52) | HTR2AHTR2CHTR2BCYP1A2CYP3A4 | |
| SCHEMBL12031043 | 0.75 | ALDH1A1 (0.46) | HTR2AHTR2CHTR2BCYP1A2CYP3A4 | |
| SCHEMBL10230451 | 0.74 | ACHE (0.45) | ACHEHRH3MEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2374795-B1 | Sulphonic acid derivatives of polycyclic dyes used for analytical applications | ATTO TEC GMBH (DE) | 2016-03-16 | — | — | EP | disclosed |
| US-9035042-B2 | Sulfonamide derivatives of polycyclic dyes used for analytical applications | ATTO-TEC GMBH (DE) | 2015-05-19 | — | — | US | disclosed |
| US-8846924-B2 | Sulfonamide derivatives of polycyclic dyes used for analytical applications | ATTO-TEC GMBH (DE) | 2014-09-30 | — | — | US | disclosed |
| EP-2332918-B1 | Sulfonamide derivatives of polycyclic dyes for analytical applications | ATTO TEC GMBH (DE) | 2014-08-06 | — | — | EP | disclosed |
| US-8614317-B2 | Sulfonamide derivatives of polycyclic dyes used for analytical applications | ATTO-TEC GMBH (DE) | 2013-12-24 | — | — | US | disclosed |
| EP-1648870-B1 | SULFONIC ACID DERIVATIVES OF POLYCYCLIC DYES USED FOR ANALYTICAL APPLICATIONS | ATTO TEC GMBH (DE) | 2011-10-19 | — | — | EP | disclosed |
| EP-2374795-A1 | Sulphonic acid derivatives of polycyclic dyes used for analytical applications | ATTO-TEC GmbH (DE) | 2011-10-12 | — | — | EP | disclosed |
| US-20110190486-A1 | SULFONAMIDE DERIVATIVES OF POLYCYCLIC DYES USED FOR ANALYTICAL APPLICATIONS | ATTO-TEC GMBH (DE) | 2011-08-04 | — | — | US | disclosed |
| US-20110172420-A1 | SULFONAMIDE DERIVATIVES OF POLYCYCLIC DYES USED FOR ANALYTICAL APPLICATIONS | ATTO-TEC GMBH (DE) | 2011-07-14 | — | — | US | disclosed |
| EP-2332918-A1 | Sulfonamide derivatives of polycyclic dyes for analytical applications | ATTO-TEC GmbH (DE) | 2011-06-15 | — | — | EP | disclosed |
| US-20060179585-A1 | Sulfonamide derviatives of polycyclic dyes used for analytical applications | ATTO-TEC GMBH (DE) | 2006-08-17 | — | — | US | disclosed |
| EP-1648870-A2 | SULFONIC ACID DERIVATIVES OF POLYCYCLIC DYES USED FOR ANALYTICAL APPLICATIONS | Atto-tec GmbH (DE) | 2006-04-26 | — | — | EP | disclosed |
| WO-2005003086-A2 | SULFONIC ACID DERIVATIVES OF POLYCYCLIC DYES USED FOR ANALYTICAL APPLICATIONS | ATTO-TEC GMBH (DE) | 2005-01-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060179585-A1 | Sulfonamide derviatives of polycyclic dyes used for analytical applications | NQO2, SQOR, QDPR | ACHE 1876/4885HTR2A 2606/4885HTR2C 2299/4885 |
| US-20110172420-A1 | SULFONAMIDE DERIVATIVES OF POLYCYCLIC DYES USED FOR ANALYTICAL APPLICATIONS | NQO2, SQOR, STS | ACHE 1869/4885HTR2A 2928/4885HTR2C 2468/4885 |
| US-20110190486-A1 | SULFONAMIDE DERIVATIVES OF POLYCYCLIC DYES USED FOR ANALYTICAL APPLICATIONS | NQO2, SQOR, STS | ACHE 1869/4885HTR2A 2928/4885HTR2C 2468/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.