SCHEMBL19165155

SCHEMBL19165155

O=C(CO)Oc1ccc(/C=C/c2cc(OC(=O)CO)cc(OC(=O)CO)c2)cc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 4/20 0.65
▸ TTR P02766 3/20 0.65
▸ KDM4E B2RXH2 2/20 0.65
▸ MEN1 O00255 2/20 0.65
▸ MAPT P10636 2/20 0.65
▸ LMNA P02545 1/20 0.65
▸ TP53 P04637 1/20 0.65
▸ CYP3A4 P08684 1/20 0.65
▸ SMN1; SMN2 Q16637 1/20 0.65
▸ CYP19A1 P11511 2/20 0.51
▸ ESR1 P03372 4/20 0.46
▸ TUBB4A P04350 3/20 0.46
▸ TUBB P07437 3/20 0.46
▸ TUBA3C P0DPH7 3/20 0.46
▸ TUBA1B P68363 3/20 0.46
▸ TUBA4A P68366 3/20 0.46
▸ TUBB4B P68371 3/20 0.46
▸ TUBB3 Q13509 3/20 0.46
▸ TUBB2A Q13885 3/20 0.46
▸ TUBB8 Q3ZCM7 3/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20786804 0.92 TTR (0.79) KMT2ATTRKDM4EMEN1MAPT
SCHEMBL19331479 0.85 PTGS2 (0.57) KMT2ATTRKDM4EMEN1MAPT
SCHEMBL20581523 0.85 KMT2A (0.68) KMT2ATTRKDM4EMEN1MAPT
SCHEMBL22141261 0.83 TTR (0.60) KMT2ATTRKDM4EMEN1MAPT
SCHEMBL28377202 0.83 TTR (0.60) KMT2ATTRKDM4EMEN1MAPT
SCHEMBL20581562 0.82 KMT2A (0.64) KMT2ATTRKDM4EMEN1MAPT
SCHEMBL19976209 0.82 KMT2A (0.59) KMT2ATTRKDM4EMEN1MAPT
SCHEMBL21819739 0.82 TTR (0.69) KMT2ATTRKDM4EMEN1MAPT
SCHEMBL28462778 0.81 KMT2A (0.82) KMT2ATTRKDM4EMEN1MAPT
SCHEMBL19039763 0.80 KMT2A (0.56) KMT2ATTRKDM4EMEN1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10851042-B2 Solubization of resveratrol glycolate and tartrate derivatives ELC MANAGEMENT LLC (US) 2020-12-01 — — US disclosed
US-20200299223-A1 SOLUBIZATION OF RESVERATROL GLYCOLATE AND TARTRATE DERIVATIVES ELC MANAGEMENT LLC 2020-09-24 — — US disclosed
US-10717698-B2 Resveratrol glycolate and tartrate derivatives and synthetic methods therefor ELC MANAGEMENT LLC (US) 2020-07-21 — — US disclosed
US-10662140-B2 Method for skin-whitening using composition containing resveratryl triglycolate KYUNGPOOK NATIONAL UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION (KR) 2020-05-26 — — US disclosed
US-20190071386-A1 RESVERATROL GLYCOLATE AND TARTRATE DERIVATIVES AND SYNTHETIC METHODS THEREFOR ELC MAN LLC (US) 2019-03-07 — — US disclosed
WO-2017155875-A1 RESVERATROL GLYCOLATE AND TARTRATE DERIVATIVES AND SYNTHETIC METHODS THEREFOR ELC MANAGEMENT LLC (US) 2017-09-14 — — WO disclosed
US-20170210694-A1 METHOD FOR SKIN-WHITENING USING COMPOSITION CONTAINING RESVERATRYL TRIGLYCOLATE KYUNGPOOK NATIONAL UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION (KR) 2017-07-27 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170210694-A1 METHOD FOR SKIN-WHITENING USING COMPOSITION CONTAINING RESVERATRYL TRIGLYCOLATE TYR, TH, MC1R KMT2A 1648/4885TTR 253/4885KDM4E 3384/4885
US-10662140-B2 Method for skin-whitening using composition containing resveratryl triglycolate TYR, TH, TREH KMT2A 1541/4885TTR 139/4885KDM4E 3394/4885
US-10851042-B2 Solubization of resveratrol glycolate and tartrate derivatives GRHPR, SORD, SUCNR1 KMT2A 4392/4885TTR 28/4885KDM4E 3625/4885
US-10717698-B2 Resveratrol glycolate and tartrate derivatives and synthetic methods therefor GRHPR, SUCNR1, TECR KMT2A 3435/4885TTR 1497/4885KDM4E 2181/4885
US-20200299223-A1 SOLUBIZATION OF RESVERATROL GLYCOLATE AND TARTRATE DERIVATIVES SORD, GRHPR, SUCNR1 KMT2A 4461/4885TTR 65/4885KDM4E 4086/4885
US-20190071386-A1 RESVERATROL GLYCOLATE AND TARTRATE DERIVATIVES AND SYNTHETIC METHODS THEREFOR GRHPR, HMGCR, SUCNR1 KMT2A 2703/4885TTR 1350/4885KDM4E 2103/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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