SCHEMBL19168248

SCHEMBL19168248

O=C(c1ccccc1)c1ccc(C2c3ccccc3-c3cc(N(c4ccccc4)c4ccccc4)ccc32)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.42
ATM Q13315 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
HPGD P15428 2/20 0.41
NPC1 O15118 1/20 0.41
RAB9A P51151 1/20 0.41
PBRM1 Q86U86 1/20 0.38
HTR2B P41595 1/20 0.37
ALDH1A1 P00352 2/20 0.36
SRD5A2 P31213 1/20 0.36
CTSL P07711 2/20 0.34
CTSK P43235 1/20 0.34
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
MAOA P21397 2/20 0.33
KDM1A O60341 1/20 0.33
MAOB P27338 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA9 Q16790 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19175935 0.87 HPGD (0.34) L3MBTL1ATMTDP1HPGDNPC1
SCHEMBL13050776 0.83 ALDH1A1 (0.45) L3MBTL1ATMTDP1HTR2BALDH1A1
SCHEMBL12455896 0.81 CYP1A2 (0.38) L3MBTL1ATMTDP1HTR2BALDH1A1
SCHEMBL23480867 0.79 ITGB1 (0.32)
SCHEMBL17950505 0.79 L3MBTL1 (0.69) L3MBTL1ATMTDP1HPGDNPC1
SCHEMBL19152313 0.77 EDNRB (0.37) L3MBTL1ATMTDP1NPC1RAB9A
SCHEMBL20010636 0.77 MAPT (0.37) L3MBTL1ATMTDP1NPC1RAB9A
SCHEMBL24031473 0.77 MAPT (0.41) L3MBTL1TDP1HPGDNPC1RAB9A
SCHEMBL14280936 0.76 ALDH1A1 (0.39) L3MBTL1ATMTDP1HTR2BALDH1A1
SCHEMBL23310483 0.75 EDNRB (0.40) L3MBTL1ATMTDP1NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170213974-A1 ORGANIC LIGHT-EMITTING DEVICE, HOST MATERIAL, LIGHT-EMITTING MATERIAL, AND COMPOUND KYULUX, INC. (JP) 2017-07-27 US disclosed
US-20170213974-A1 ORGANIC LIGHT-EMITTING DEVICE, HOST MATERIAL, LIGHT-EMITTING MATERIAL, AND COMPOUND KYULUX, INC. (JP) 2017-07-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170213974-A1 ORGANIC LIGHT-EMITTING DEVICE, HOST MATERIAL, LIGHT-EMITTING MATERIAL, AND COMPOUND CRY1, CRY2, CYBA L3MBTL1 251/4885ATM 3303/4885TDP1 1930/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.