Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PHF8 | Q9UPP1 | 5/20 | 0.43 |
| ▸ | KDM2A | Q9Y2K7 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.41 |
| ▸ | EGLN1 | Q9GZT9 | 5/20 | 0.38 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.38 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.38 |
| ▸ | KDM5C | P41229 | 3/20 | 0.35 |
| ▸ | KDM6B | O15054 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | KDM4A | O75164 | 1/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.34 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.33 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | GABRP | O00591 | 2/20 | 0.31 |
| ▸ | GABRD | O14764 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21012648 | 0.89 | PHF8 (0.52) | PHF8KDM2ALMNASLC15A2EGLN1 | |
| SCHEMBL18908612 | 0.89 | LMNA (0.47) | PHF8KDM2ALMNASLC15A2EGLN1 | |
| Succinic Acid SCHEMBL2596564 | 0.68 | LMNA (0.69) | PHF8KDM2ALMNASLC15A2EGLN1 | |
| Succinic Acid SCHEMBL5875148 | 0.68 | EGLN1 (0.69) | PHF8KDM2ALMNASLC15A2EGLN1 | |
| Succinic Acid SCHEMBL5875155 | 0.68 | EGLN1 (0.69) | PHF8KDM2ALMNASLC15A2EGLN1 | |
| Succinic Acid SCHEMBL27514653 | 0.65 | LMNA (0.75) | PHF8KDM2ALMNASLC15A2EGLN1 | |
| Succinic Acid SCHEMBL35204 | 0.65 | EGLN1 (0.75) | PHF8KDM2ALMNASLC15A2EGLN1 | |
| Succinic Acid SCHEMBL2148509 | 0.65 | EGLN1 (0.75) | PHF8KDM2ALMNASLC15A2EGLN1 | |
| Succinic Acid SCHEMBL1921951 | 0.65 | EGLN1 (0.75) | PHF8KDM2ALMNASLC15A2EGLN1 | |
| Succinic Acid SCHEMBL17975779 | 0.65 | EGLN1 (0.75) | PHF8KDM2ALMNASLC15A2EGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170209595-A1 | DISULFUR BRIDGE LINKERS FOR CONJUGATION OF A CELL-BINDING MOLECULE | SUZHOU M-CONJ BIOTECH CO., LTD. (CN) | 2017-07-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170209595-A1 | DISULFUR BRIDGE LINKERS FOR CONJUGATION OF A CELL-BINDING MOLECULE | CD74, CD2, EPCAM | PHF8 2079/4885KDM2A 2796/4885LMNA 4757/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.