Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 11/20 | 0.45 |
| ▸ | ADRB1 | P08588 | 7/20 | 0.43 |
| ▸ | MPO | P05164 | 5/20 | 0.40 |
| ▸ | ADRB3 | P13945 | 5/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | FPR3 | P25089 | 1/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.39 |
| ▸ | HTR1D | P28221 | 1/20 | 0.39 |
| ▸ | HTR1B | P28222 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | GPR183 | P32249 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19174337 | 1.00 | ADRB2 (0.45) | ADRB2ADRB1MPOADRB3SLC6A4 | |
| SCHEMBL15107034 | 0.91 | MPO (0.43) | ADRB2ADRB1MPOADRB3SLC6A4 | |
| SCHEMBL6857021 | 0.81 | MPO (0.48) | ADRB2ADRB1MPOADRB3SLC6A4 | |
| SCHEMBL17011674 | 0.80 | ACLY (0.35) | MPOSLC6A4HTR1AKCNH2TMEM97 | |
| SCHEMBL17011675 | 0.80 | ACLY (0.35) | MPOSLC6A4HTR1AKCNH2TMEM97 | |
| SCHEMBL23940684 | 0.79 | ACLY (0.36) | ADRB2ADRB1MPOSLC6A4HTR1A | |
| SCHEMBL12397446 | 0.79 | ACLY (0.36) | ADRB2ADRB1MPOSLC6A4HTR1A | |
| SCHEMBL18697459 | 0.79 | ACLY (0.36) | ADRB2ADRB1MPOSLC6A4HTR1A | |
| SCHEMBL19174208 | 0.75 | MPO (0.63) | MPOSLC6A4CA12CA2CA9 | |
| SCHEMBL14240235 | 0.72 | ADRB2 (0.68) | ADRB2ADRB1ADRB3SLC6A4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3405467-B1 | PROCESS FOR THE SYNTHESIS OF INTERMEDIATES OF NEBIVOLOL | MENARINI INT OPERATIONS LUXEMBOURG SA (LU) | 2021-08-04 | — | — | EP | disclosed |
| WO-2017125900-A1 | PROCESS FOR THE SYNTHESIS OF INTERMEDIATES OF NEBIVOLOL | MENARINI INTERNATIONAL OPERATIONS LUXEMBOURG S.A. (LU) | 2017-07-27 | — | — | WO | disclosed |