Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 1/20 | 0.36 |
| ▸ | MPO | P05164 | 3/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.33 |
| ▸ | CA3 | P07451 | 1/20 | 0.33 |
| ▸ | CA6 | P23280 | 1/20 | 0.33 |
| ▸ | CA5A | P35218 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.33 |
| ▸ | TYR | P14679 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | XBP1 | P17861 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18697459 | 1.00 | ACLY (0.36) | ACLYMPOKCNH2ADRB2CA3 | |
| SCHEMBL12397446 | 1.00 | ACLY (0.36) | ACLYMPOKCNH2ADRB2CA3 | |
| SCHEMBL17011675 | 0.86 | ACLY (0.35) | ACLYMPOKCNH2CA3CA6 | |
| SCHEMBL17011674 | 0.86 | ACLY (0.35) | ACLYMPOKCNH2CA3CA6 | |
| SCHEMBL20006876 | 0.83 | KCNH2 (0.38) | MPOKCNH2ADRB2ADRB1TMEM97 | |
| SCHEMBL11943723 | 0.80 | SLC6A2 (0.45) | SLC6A4LMNA | |
| SCHEMBL19174337 | 0.79 | ADRB2 (0.45) | MPOKCNH2ADRB2CA9HTR1A | |
| SCHEMBL19174286 | 0.79 | ADRB2 (0.45) | MPOKCNH2ADRB2CA9HTR1A | |
| SCHEMBL12632952 | 0.78 | TYR (0.46) | MPOCA3CA6CA5ACA9 | |
| SCHEMBL24317052 | 0.77 | KCNH2 (0.31) | MPOKCNH2ADRB2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3299364-B1 | NEBIVOLOL SYNTHESIS METHOD AND INTERMEDIATE COMPOUND THEREOF | ZHEJIANG AUSUN PHARMACEUTICAL CO LTD (CN) | 2021-10-20 | — | — | EP | disclosed |