Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | NQO2 | P16083 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1918902 | 0.87 | ADORA1 (0.51) | ADORA1KMT2AADORA3ADORA2ANQO2 | |
| SCHEMBL13907870 | 0.83 | KMT2A (0.40) | ADORA1KMT2AADORA3ADORA2AKDM4E | |
| SCHEMBL31459666 | 0.82 | TDP1 (0.38) | ADORA1KMT2ANQO2 | |
| SCHEMBL25110136 | 0.79 | ADORA1 (0.37) | ADORA1KMT2AADORA3ADORA2AKDM4E | |
| SCHEMBL3712699 | 0.77 | KMT2A (0.38) | ADORA1KMT2AADORA3ADORA2AKDM4E | |
| SCHEMBL9754821 | 0.77 | ADORA1 (0.36) | ADORA1KMT2AADORA3ADORA2AKDM4E | |
| SCHEMBL158113 | 0.76 | APEX1 (0.41) | ADORA1KMT2AADORA3ADORA2AKDM4E | |
| SCHEMBL16801763 | 0.75 | NQO2 (0.42) | ADORA1ADORA3ADORA2AKDM4ENQO2 | |
| SCHEMBL7386115 | 0.74 | ADORA1 (0.53) | ADORA1KMT2AADORA3ADORA2AKDM4E | |
| SCHEMBL1918148 | 0.74 | EGLN1 (0.40) | KMT2AKDM4ENQO2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10077242-B2 | Convergent approach to the total synthesis of telmisartan via a suzuki cross-coupling reaction | VIRGINIA COMMONWEALTH UNIVERSITY (US) | 2018-09-18 | — | — | US | claimed |
| US-20170260146-A1 | A CONVERGENT APPROACH TO THE TOTAL SYNTHESIS OF TELMISARTAN VIA A SUZUKI CROSS-COUPLING REACTION | VIRGINIA COMMONWEALTH UNIVERSITY | 2017-09-14 | — | — | US | claimed |
| WO-2016089845-A1 | A CONVERGENT APPROACH TO THE TOTAL SYNTHESIS OF TELMISARTAN VIA A SUZUKI CROSS-COUPLING REACTION | VIRGINIA COMMONWEALTH UNIVERSITY (US) | 2016-06-09 | — | — | WO | claimed |
| WO-2010081670-A2 | PROCESS FOR THE PREPARATION OF BENZIMIDAZOLES | LONZA LTD (CH) | 2010-07-22 | — | — | WO | claimed |
| EP-3081213-B1 | TRICYCLIC COMPOUND | KYOWA KIRIN CO LTD (JP) | 2020-04-01 | — | — | EP | disclosed |
| US-10077242-B2 | Convergent approach to the total synthesis of telmisartan via a suzuki cross-coupling reaction | VIRGINIA COMMONWEALTH UNIVERSITY (US) | 2018-09-18 | — | — | US | disclosed |
| US-20170260146-A1 | A CONVERGENT APPROACH TO THE TOTAL SYNTHESIS OF TELMISARTAN VIA A SUZUKI CROSS-COUPLING REACTION | VIRGINIA COMMONWEALTH UNIVERSITY | 2017-09-14 | — | — | US | disclosed |
| US-9475805-B2 | Tricyclic compound | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2016-10-25 | — | — | US | disclosed |
| EP-3081213-A1 | TRICYCLIC COMPOUND | Kyowa Hakko Kirin Co., Ltd. (JP) | 2016-10-19 | — | — | EP | disclosed |
| WO-2016089845-A1 | A CONVERGENT APPROACH TO THE TOTAL SYNTHESIS OF TELMISARTAN VIA A SUZUKI CROSS-COUPLING REACTION | VIRGINIA COMMONWEALTH UNIVERSITY (US) | 2016-06-09 | — | — | WO | disclosed |
| US-20150291587-A1 | TRICYCLIC COMPOUND | KYOWA KIRIN CO., LTD. (JP) | 2015-10-15 | — | — | US | disclosed |
| US-20130267711-A1 | TRICYCLIC COMPOUND | KYOWA HAKKO KIRIN CO LTD (JP) | 2013-10-10 | — | — | US | disclosed |
| US-8486980-B2 | Tricyclic compound | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2013-07-16 | — | — | US | disclosed |
| US-20110201640-A1 | TRICYCLIC COMPOUND | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2011-08-18 | — | — | US | disclosed |
| EP-2327690-A1 | TRICYCLIC COMPOUND | Kyowa Hakko Kirin Co., Ltd. (JP) | 2011-06-01 | — | — | EP | disclosed |
| WO-2010081670-A2 | PROCESS FOR THE PREPARATION OF BENZIMIDAZOLES | LONZA LTD (CH) | 2010-07-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10077242-B2 | Convergent approach to the total synthesis of telmisartan via a suzuki cross-coupling reaction | AGTR2, AGTR1, REN | ADORA1 3746/4885KMT2A 1707/4885ADORA3 3257/4885 |
| US-20150291587-A1 | TRICYCLIC COMPOUND | PPARA, PPARG, PPARD | ADORA1 450/4885KMT2A 2018/4885ADORA3 654/4885 |
| US-20130267711-A1 | TRICYCLIC COMPOUND | PPARA, PPARG, PPARD | ADORA1 450/4885KMT2A 2018/4885ADORA3 654/4885 |
| US-20110201640-A1 | TRICYCLIC COMPOUND | PPARG, PPARA, PPARD | ADORA1 1219/4885KMT2A 1675/4885ADORA3 1519/4885 |
| US-20170260146-A1 | A CONVERGENT APPROACH TO THE TOTAL SYNTHESIS OF TELMISARTAN VIA A SUZUKI CROSS-COUPLING REACTION | REN, AGTR1, AGTR2 | ADORA1 3868/4885KMT2A 1832/4885ADORA3 3482/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.