Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 4/20 | 0.57 |
| ▸ | CA6 | P23280 | 4/20 | 0.57 |
| ▸ | CA7 | P43166 | 4/20 | 0.57 |
| ▸ | CA9 | Q16790 | 4/20 | 0.57 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.57 |
| ▸ | CA5B | Q9Y2D0 | 4/20 | 0.57 |
| ▸ | CA2 | P00918 | 3/20 | 0.57 |
| ▸ | CA4 | P22748 | 3/20 | 0.57 |
| ▸ | CA5A | P35218 | 3/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | CASP2 | P42575 | 2/20 | 0.57 |
| ▸ | F13A1 | P00488 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | THPO | P40225 | 2/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.57 |
| ▸ | RECQL | P46063 | 2/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL831497 | 1.00 | CA12 (0.57) | CA12CA6CA7CA9CA14 | |
| SCHEMBL19179134 | 0.98 | TDP1 (0.58) | CA12CA6CA7CA9CA14 | |
| SCHEMBL19179346 | 0.98 | CASP2 (0.62) | CA12CA6CA7CA9CA14 | |
| SCHEMBL5145932 | 0.95 | CA12 (0.52) | CA12CA6CA7CA9CA14 | |
| SCHEMBL19179347 | 0.95 | CASP2 (0.59) | CA12CA6CA7CA9CA14 | |
| SCHEMBL19179129 | 0.95 | CYP2C19 (0.50) | CA12CA6CA7CA9CA14 | |
| SCHEMBL8766714 | 0.92 | CYP2C19 (0.54) | CA12CA6CA7CA9CA14 | |
| SCHEMBL832891 | 0.92 | TDP1 (0.62) | CA12CA6CA7CA9CA14 | |
| SCHEMBL4143342 | 0.90 | CA12 (0.57) | CA12CA6CA7CA9CA14 | |
| SCHEMBL13336449 | 0.90 | CA12 (0.65) | CA12CA6CA7CA9CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10899985-B2 | Amine alkenyl substituted succinimide reaction product fuel additives, compositions, and methods | EVONIK OPERATIONS GMBH (DE) | 2021-01-26 | — | — | US | claimed |
| US-10899986-B2 | Substituted Mannich base fuel additives, compositions, and methods | EVONIK OPERATIONS GMBH (DE) | 2021-01-26 | — | — | US | claimed |
| US-10676564-B2 | Amidoamine and polyamide curing agents, compositions, and methods | EVONIK OPERATIONS GMBH (DE) | 2020-06-09 | — | — | US | claimed |
| EP-3504303-B1 | SUBSTITUTED MANNICH BASE FUEL ADDITIVES, COMPOSITIONS, AND METHODS | EVONIK OPERATIONS GMBH (DE) | 2020-04-01 | — | — | EP | claimed |
| EP-3411421-B1 | AMIDOAMINE AND POLYAMIDE CURING AGENTS, COMPOSITIONS, AND METHODS | EVONIK OPERATIONS GMBH (DE) | 2019-12-25 | — | — | EP | claimed |
| EP-3504303-A1 | SUBSTITUTED MANNICH BASE FUEL ADDITIVES, COMPOSITIONS, AND METHODS | Evonik Degussa GmbH (DE) | 2019-07-03 | — | — | EP | claimed |
| EP-3504304-A1 | AMINE ALKENYL SUBSTITUTED SUCCINIMIDE REACTION PRODUCT FUEL ADDITIVES, COMPOSITIONS, AND METHODS | Evonik Degussa GmbH (DE) | 2019-07-03 | — | — | EP | claimed |
| US-20190169515-A1 | SUBSTITUTED MANNICH BASE FUEL ADDITIVES, COMPOSITIONS, AND METHODS | EVONIK OPERATIONS GMBH (DE) | 2019-06-06 | — | — | US | claimed |
| US-20190169514-A1 | AMINE ALKENYL SUBSTITUTED SUCCINIMIDE REACTION PRODUCT FUEL ADDITIVES, COMPOSITIONS, AND METHODS | EVONIK OPERATIONS GMBH (DE) | 2019-06-06 | — | — | US | claimed |
| EP-3411421-A1 | AMIDOAMINE AND POLYAMIDE CURING AGENTS, COMPOSITIONS, AND METHODS | Evonik Degussa GmbH (DE) | 2018-12-12 | — | — | EP | claimed |
| WO-2018039563-A1 | SUBSTITUTED MANNICH BASE FUEL ADDITIVES, COMPOSITIONS, AND METHODS | EVONIK DEGUSSA GMBH (DE) | 2018-03-01 | — | — | WO | claimed |
| WO-2018039571-A1 | AMINE ALKENYL SUBSTITUTED SUCCINIMIDE REACTION PRODUCT FUEL ADDITIVES, COMPOSITIONS, AND METHODS | EVONIK DEGUSSA GMBH (DE) | 2018-03-01 | — | — | WO | claimed |
| WO-2017136333-A1 | AMIDOAMINE AND POLYAMIDE CURING AGENTS, COMPOSITIONS, AND METHODS | EVONIK DEGUSSA GMBH (DE) | 2017-08-10 | — | — | WO | claimed |
| US-20170218115-A1 | AMIDOAMINE AND POLYAMIDE CURING AGENTS, COMPOSITIONS, AND METHODS | EVONIK OPERATIONS GMBH (DE) | 2017-08-03 | — | — | US | claimed |
| US-20250223449-A1 | COATINGS | JOTUN A/S (NO) | 2025-07-10 | — | — | US | disclosed |
| US-20250163293-A1 | COATING COMPOSITION | JOTUN A/S (NO) | 2025-05-22 | — | — | US | disclosed |
| WO-2025051850-A1 | ANTIFOULING COATING SYSTEM | JOTUN A/S (NO) | 2025-03-13 | — | — | WO | disclosed |
| US-20170240691-A1 | BENZYLATED MANNICH BASE CURING AGENTS, COMPOSITIONS, AND METHODS | EVONIK OPERATIONS GMBH (DE) | 2017-08-24 | — | — | US | disclosed |
| WO-2017136333-A1 | AMIDOAMINE AND POLYAMIDE CURING AGENTS, COMPOSITIONS, AND METHODS | EVONIK DEGUSSA GMBH (DE) | 2017-08-10 | — | — | WO | disclosed |
| US-20170218115-A1 | AMIDOAMINE AND POLYAMIDE CURING AGENTS, COMPOSITIONS, AND METHODS | EVONIK OPERATIONS GMBH (DE) | 2017-08-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10899986-B2 | Substituted Mannich base fuel additives, compositions, and methods | H1-2, H1-0, H1-3 | CA12 550/4885CA6 2936/4885CA7 2124/4885 |
| US-10676564-B2 | Amidoamine and polyamide curing agents, compositions, and methods | NAAA, FAAH2, H1-2 | CA12 2527/4885CA6 3163/4885CA7 2744/4885 |
| US-20170240691-A1 | BENZYLATED MANNICH BASE CURING AGENTS, COMPOSITIONS, AND METHODS | H1-0, SRM, H1-2 | CA12 2279/4885CA6 4127/4885CA7 2504/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.