SCHEMBL19181752

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL19180943	0.90	NLRP3 (0.52)	SMN1; SMN2ANO1RORCKCNJ5KCNJ3
	SCHEMBL19179625	0.88	P2RX7 (0.46)	HPGDNPC1RAB9ARORCHSD11B1
	SCHEMBL19288855	0.85	GAA (0.43)	GAAKDM4ESMN1; SMN2CA12CA1
	SCHEMBL19179851	0.83	RAB9A (0.51)	GAASMN1; SMN2ALDH1A1HPGDNPC1
	SCHEMBL19179565	0.79	L3MBTL1 (0.57)	GAASMN1; SMN2HPGDNPC1RAB9A
	SCHEMBL19181907	0.78	MCHR1 (0.47)	—
	SCHEMBL19181906	0.78	L3MBTL1 (0.47)	GAASMN1; SMN2ALDH1A1NPC1RAB9A
	SCHEMBL3603325	0.73	CA12 (0.52)	GAAKDM4ESMN1; SMN2CA12CA1
	SCHEMBL19179705	0.73	MTOR (0.52)	SMN1; SMN2CA1CA2CA9
	SCHEMBL19179849	0.73	NPC1 (0.51)	GAASMN1; SMN2CA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.