Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 1/20 | 0.43 |
| ▸ | MALT1 | Q9UDY8 | 5/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | NTRK1 | P04629 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19187348 | 0.88 | SLC9A1 (0.41) | SLC9A1MALT1LMNANTRK1MAPT | |
| SCHEMBL19188095 | 0.83 | MET (0.43) | SLC9A1MALT1LMNANTRK1MAPT | |
| SCHEMBL15218573 | 0.82 | LMNA (0.55) | SLC9A1LMNAMAPTMEN1KMT2A | |
| SCHEMBL15209784 | 0.80 | SMN1; SMN2 (0.50) | SLC9A1MALT1LMNAMAPTHTT | |
| SCHEMBL20028704 | 0.78 | SLC9A1 (0.47) | SLC9A1MALT1LMNAMAPTHTT | |
| SCHEMBL15209967 | 0.77 | CYP2C9 (0.46) | LMNAMAPTHTTL3MBTL1ALDH1A1 | |
| SCHEMBL19186998 | 0.77 | MAPT (0.36) | SLC9A1MALT1LMNAMAPTHTT | |
| SCHEMBL19188109 | 0.77 | ALDH1A1 (0.39) | SLC9A1MALT1LMNANTRK1MAPT | |
| SCHEMBL19187040 | 0.77 | MALT1 (0.37) | SLC9A1MALT1LMNAMAPTHTT | |
| SCHEMBL15209797 | 0.76 | ALDH1A1 (0.45) | MALT1LMNAHTTNPY5RALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3263564-B1 | AZA-ARYL 1H-PYRAZOL-1-YL BENZENE SULFONAMIDES AS CCR(9) ANTAGONISTS | CHEMOCENTRYX INC (US) | 2020-06-10 | — | — | EP | disclosed |
| EP-2820006-B1 | PYRAZOL-1-YL BENZENE SULFONAMIDES AS CCR9 ANTAGONISTS | CHEMOCENTRYX INC (US) | 2017-08-02 | — | — | EP | disclosed |