SCHEMBL191888

SCHEMBL191888

O=C1C=C(c2cccs2)C(=O)N1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A11 P48066 1/20 0.41
LTK P29376 1/20 0.40
CDK5 Q00535 1/20 0.40
MST1R Q04912 1/20 0.40
DYRK1A Q13627 1/20 0.40
CLK4 Q9HAZ1 1/20 0.40
GSK3B P49841 2/20 0.40
EGFR P00533 1/20 0.38
RET P07949 1/20 0.38
KDR P35968 1/20 0.38
CTRC Q99895 1/20 0.38
HPGD P15428 4/20 0.38
KDM4E B2RXH2 3/20 0.38
PKM P14618 1/20 0.38
MAOA P21397 2/20 0.38
TYMP P19971 1/20 0.38
ERCC1 P07992 2/20 0.36
FEN1 P39748 2/20 0.36
ERCC4 Q92889 2/20 0.36
NPY5R Q15761 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cysteine SCHEMBL13858126 0.80 PTGS1 (0.39) HPGDKDM4EPKMERCC1FEN1
SCHEMBL16369828 0.71 GSK3B (0.56) SLC6A11LTKCDK5MST1RDYRK1A
SCHEMBL9587810 0.71 GSK3B (0.37) GSK3B
SCHEMBL28419075 0.69 SLC6A11 (0.41) SLC6A11LTKCDK5MST1RDYRK1A
SCHEMBL121405 0.69 GSK3B (0.50) LTKGSK3BKDM4EMAOAMAOB
SCHEMBL27664385 0.69 GSK3B (0.50) LTKGSK3BKDM4EMAOAMAOB
Phthalimide SCHEMBL16027142 0.68 GSK3B (0.62) SLC6A11LTKCDK5MST1RDYRK1A
SCHEMBL5146143 0.68 PGR (0.40) LTKCDK5MST1RDYRK1ACLK4
SCHEMBL167973 0.68 SLC6A11 (0.44) SLC6A11LTKCDK5MST1RDYRK1A
SCHEMBL2397573 0.68 GSK3B (0.47) SLC6A11LTKCDK5MST1RDYRK1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 4099 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122080237-A Preparation method of ovarian stem cells and application of ovarian stem cells in preparation of ovarian anti-aging drugs 2026-05-26 CN claimed
CN-122005851-A Vagus nerve double-targeting delivery vehicle and preparation method and application thereof 中国科学院苏州纳米技术与纳米仿生研究所 2026-05-12 CN claimed
CN-122011723-A Photoresponse protein hydrogel with wide-range mechanical regulation characteristic and preparation method thereof 济南微生态生物医学省实验室 2026-05-12 CN claimed
EP-4724455-A1 MULTIVALENT BINDING UNIT MODIFIED DIDEOXYNUCLEOTIDE TRIPHOSPHATES AND METHODS OF MAKING AND USING THE SAME ILLUMINA, INC. (US) 2026-04-15 EP claimed
EP-4717780-A2 QUANTITATIVE MASSIVELY PARALLEL PROTEOMICS Verily Life Sciences LLC (US) 2026-04-01 EP claimed
EP-3488239-B1 QUANTITATIVE MASSIVELY PARALLEL PROTEOMICS VERILY LIFE SCIENCES LLC (US) 2026-03-25 EP claimed
US-20260071270-A1 ON-SEQUENCER IMAGING FLOWCELL REUSE ILLUMINA, INC. (US) 2026-03-12 US claimed
EP-4705506-A1 CONTROLLED POLYNUCLEOTIDE TRANSLOCATION IN NANOPORE SEQUENCING Illumina, Inc. (US) 2026-03-11 EP claimed
US-20260063518-A1 DEVICE FOR TRAPPING RARE CELLS FROM FLUID SAMPLES KEDARISETTI PRADYUMNA (CA) 2026-03-05 US claimed
WO-2026043922-A1 MODIFIED NUCLEOTIDES AND RELATED METHODS FOR NANOPORE SEQUENCING ILLUMINA, INC. (US) 2026-02-26 WO claimed
US-8501486-B2 Materials and methods for isolating phosphopeptides PURDUE RESEARCH FOUNDATION (US) 2013-08-06 US claimed
US-20120282652-A1 PREPARATION OF PEPTIDE MIXTURES BY PROTEASE CATALYSIS DESIGNED TO PROVIDE USEFUL BIOLOGICAL AND PHYSICAL PROPERTIES POLYTECHNIC INSTITUTE OF NEW YORK UNIVERSITY (US) 2012-11-08 US claimed
WO-2012118780-A2 PREPARATION OF PEPTIDE MIXTURES BY PROTEASE CATALYSIS DESIGNED TO PROVIDE USEFUL BIOLOGICAL AND PHYSICAL PROPERTIES POLYTECHNIC INSTITUTE OF NEW YORK UNIVERSITY (US) 2012-09-07 WO claimed
WO-2012048009-A2 NANOSTRUCTURED PHYSICALLY-ASSOCIATING HYDROGELS FOR INJECTABLE, RESPONSIVE AND TOUGH BIOMATERIALS MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2012-04-12 WO claimed
US-20100087008-A1 Materials and Methods for Isolating Phosphopeptides PURDUE RESEARCH FOUNDATION 2010-04-08 US claimed
US-20090118140-A1 METHOD AND SYSTEM FOR ASSEMBLY OF MACROMOLECULES AND NANOSTRUCTURES XF TECHNOLOGIES INC. 2009-05-07 US claimed
WO-2008112980-A2 METHOD AND SYSTEM FOR ASSEMBLY OF MACROMOLECULES AND NANOSTRUCTURES INCITOR, LLC (US) 2008-09-18 WO claimed
JP-2007525967-A 2007-09-13 JP claimed
EP-1639093-A2 MODIFIED MOLECULAR BEACONS Georgia Tech Research Corporation (US) 2006-03-29 EP claimed
WO-2005021712-A2 MODIFIED MOLECULAR BEACONS GEORGIA TECH RESEARCH CORPORATION (US) 2005-03-10 WO claimed