Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CASP6 | P55212 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19193445 | 0.88 | ALDH1A1 (0.40) | ALDH1A1KDM4EGLAHTTMAOB | |
| SCHEMBL19193170 | 0.85 | ALDH1A1 (0.46) | ALDH1A1KDM4EGLAHTTMAOB | |
| SCHEMBL5583377 | 0.83 | MAOB (0.57) | ALDH1A1HTTMAOBNPSR1SMN1; SMN2 | |
| SCHEMBL19193109 | 0.82 | SNCA (0.54) | ALDH1A1KDM4EGLAHTTSMN1; SMN2 | |
| SCHEMBL19193210 | 0.80 | KDM4E (0.38) | ALDH1A1KDM4EGLAHTTSMN1; SMN2 | |
| SCHEMBL13839051 | 0.80 | RAB9A (0.51) | ALDH1A1KDM4EHTTSMN1; SMN2LMNA | |
| SCHEMBL19193261 | 0.79 | GPR35 (0.38) | ALDH1A1KDM4EGLAHTTSMN1; SMN2 | |
| SCHEMBL19193185 | 0.79 | GPR35 (0.38) | ALDH1A1KDM4EGLAHTTSMN1; SMN2 | |
| SCHEMBL19193104 | 0.78 | ALDH1A1 (0.42) | ALDH1A1KDM4EGLAHTTMAOB | |
| SCHEMBL19193342 | 0.78 | GPR35 (0.42) | ALDH1A1KDM4EGLAHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170217997-A1 | PHOTO-CLEAVABLE PRIMER COMPOSITIONS AND METHODS OF USE | ORMCO CORPORATION | 2017-08-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170217997-A1 | PHOTO-CLEAVABLE PRIMER COMPOSITIONS AND METHODS OF USE | SP1, GPER1, ESR1 | ALDH1A1 869/4885KDM4E 2111/4885GLA 139/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.