Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20548567 | 0.90 | MAOB (0.56) | MAOBALDH1A1HTTNPSR1TSHR | |
| SCHEMBL18919691 | 0.87 | ALDH1A1 (0.50) | MAOBALDH1A1HTTNPSR1TSHR | |
| SCHEMBL5583251 | 0.85 | MAOB (0.53) | MAOBALDH1A1HTTNPSR1TSHR | |
| SCHEMBL5604684 | 0.85 | MAOB (0.53) | MAOBALDH1A1HTTNPSR1TSHR | |
| SCHEMBL12611778 | 0.84 | MAOB (0.53) | MAOBALDH1A1HTTNPSR1TSHR | |
| SCHEMBL19193136 | 0.83 | ALDH1A1 (0.48) | MAOBALDH1A1HTTNPSR1TSHR | |
| SCHEMBL1108184 | 0.83 | MAOB (0.61) | MAOBALDH1A1HTTTSHRKMT2A | |
| SCHEMBL13883939 | 0.82 | MAOB (0.51) | MAOBALDH1A1HTTNPSR1TSHR | |
| SCHEMBL286962 | 0.82 | MAOB (0.56) | MAOBALDH1A1HTTTSHRKMT2A | |
| SCHEMBL17938431 | 0.82 | NPC1 (0.49) | ALDH1A1NPSR1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10011603-B2 | Process for preparing a carbapenem antibiotic | JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) | 2018-07-03 | — | — | US | disclosed |
| US-20170210744-A1 | PROCESS FOR PREPARING A CARBAPENEM ANTIBIOTIC | JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) | 2017-07-27 | — | — | US | disclosed |
| US-20170210744-A1 | PROCESS FOR PREPARING A CARBAPENEM ANTIBIOTIC | JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) | 2017-07-27 | — | — | US | disclosed |
| US-7301049-B2 | Photolabile esters and their uses | THE INSTITUTE OF CANCER RESEARCH (GB) | 2007-11-27 | — | — | US | disclosed |
| US-6866981-B2 | Mixture of cationic polymer containing unsaturated aromatic compound and sulfonated aromatic compound, photoinitiator and acid generator | MITSUBISHI PAPER MILLS LIMITED (JP) | 2005-03-15 | — | — | US | disclosed |
| US-20040242653-A1 | Photolabile esters and their uses | THE INSTITUTE OF CANCER RESEARCH (GB) | 2004-12-02 | — | — | US | disclosed |
| EP-1399412-A1 | PHOTOLABILE ESTERS AND THEIR USES | The Institute of Cancer Research (GB) | 2004-03-24 | — | — | EP | disclosed |
| US-20030190548-A1 | Mixture of cationic polymer containing unsaturated aromatic compound and sulfonated aromatic compound, photoinitiator and acid generator | MITSUBISHI PAPER MILLS LIMITED (JP) | 2003-10-09 | — | — | US | disclosed |
| WO-2003000644-A1 | PHOTOLABILE ESTERS AND THEIR USES | THE INSTITUTE OF CANCER RESEARCH (GB) | 2003-01-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10011603-B2 | Process for preparing a carbapenem antibiotic | MGAM, HAMP, MB | MAOB 2362/4885ALDH1A1 3271/4885HTT 4009/4885 |
| US-20170210744-A1 | PROCESS FOR PREPARING A CARBAPENEM ANTIBIOTIC | MGAM, HAMP, MB | MAOB 2362/4885ALDH1A1 3271/4885HTT 4009/4885 |
| US-20040242653-A1 | Photolabile esters and their uses | DIMT1, DCTD, DTYMK | MAOB 1362/4885ALDH1A1 2920/4885HTT 2457/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.