Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 2/20 | 0.42 |
| ▸ | CASP2 | P42575 | 1/20 | 0.42 |
| ▸ | NAAA | Q02083 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 5/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.37 |
| ▸ | KDM4A | O75164 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.37 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.37 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.36 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5200684 | 0.85 | DNM1 (0.48) | DNM1CASP2NAAAFAAHEPHX2 | |
| SCHEMBL14229463 | 0.74 | EPHX2 (0.48) | EPHX2 | |
| SCHEMBL3370091 | 0.74 | EPHX2 (0.51) | EPHX2 | |
| SCHEMBL24415729 | 0.70 | CASP2 (0.62) | DNM1CASP2NAAAFAAHEPHX2 | |
| SCHEMBL14229927 | 0.70 | EPHX2 (0.42) | EPHX2 | |
| SCHEMBL18313754 | 0.70 | CASP2 (0.67) | DNM1CASP2NAAAFAAHEPHX2 | |
| SCHEMBL24415182 | 0.70 | CASP2 (0.67) | DNM1CASP2NAAAFAAHEPHX2 | |
| SCHEMBL25894622 | 0.69 | CASP2 (0.71) | DNM1CASP2NAAAFAAHEPHX2 | |
| SCHEMBL21419232 | 0.69 | CASP2 (0.57) | DNM1CASP2NAAAFAAHEPHX2 | |
| SCHEMBL23468563 | 0.69 | CASP2 (0.61) | DNM1CASP2NAAAFAAHEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170218367-A1 | NUCLEIC ACID AMPHIPHILES AND NANOSTRUCTURES | REGENTS OF THE UNIVERSITY OF MINNESOTA | 2017-08-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170218367-A1 | NUCLEIC ACID AMPHIPHILES AND NANOSTRUCTURES | EWSR1, ANXA4, POLRMT | DNM1 152/4885CASP2 1184/4885NAAA 1607/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.