Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 4/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.64 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.41 |
| ▸ | PLA2G10 | O15496 | 2/20 | 0.39 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.39 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.39 |
| ▸ | ASAH2 | Q9NR71 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.38 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10422178 | 0.94 | MEN1 (0.57) | FAAHMEN1MAPK1KMT2APLA2G10 | |
| SCHEMBL10727436 | 0.82 | CA12 (0.50) | MEN1KMT2A | |
| SCHEMBL8015904 | 0.82 | CA12 (0.50) | MEN1KMT2A | |
| SCHEMBL10727061 | 0.82 | CA12 (0.50) | MEN1KMT2A | |
| SCHEMBL6708723 | 0.82 | CA12 (0.50) | MEN1KMT2A | |
| SCHEMBL26037662 | 0.82 | CASP2 (0.58) | FAAHEPHX1DNM1 | |
| SCHEMBL15397334 | 0.81 | HSP90AA1 (0.41) | FAAHMEN1MAPK1KMT2ADNM1 | |
| SCHEMBL585370 | 0.81 | CASP2 (0.56) | FAAHEPHX1DNM1 | |
| SCHEMBL22204477 | 0.80 | CTSD (0.48) | FAAHDNM1HSP90AA1 | |
| SCHEMBL15397314 | 0.80 | FAAH (0.61) | FAAHDNM1HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170218367-A1 | NUCLEIC ACID AMPHIPHILES AND NANOSTRUCTURES | REGENTS OF THE UNIVERSITY OF MINNESOTA | 2017-08-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170218367-A1 | NUCLEIC ACID AMPHIPHILES AND NANOSTRUCTURES | EWSR1, ANXA4, POLRMT | FAAH 3376/4885MEN1 1926/4885MAPK1 4115/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.