Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CPN1 | P15169 | 1/20 | 0.40 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 4/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ACACB | O00763 | 1/20 | 0.35 |
| ▸ | ACACA | Q13085 | 1/20 | 0.35 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11916105 | 0.94 | KDM4E (0.38) | MEN1KMT2ACPN1CPB2KDM4E | |
| SCHEMBL26138844 | 0.84 | MEN1 (0.40) | MEN1KMT2AKDM4ECYP2C9CYP2C19 | |
| SCHEMBL16133057 | 0.83 | SIGMAR1 (0.38) | MEN1KMT2ACPN1CPB2KDM4E | |
| SCHEMBL19203542 | 0.82 | ACHE (0.50) | MEN1KMT2ACPN1CPB2KDM4E | |
| SCHEMBL19196470 | 0.82 | SIGMAR1 (0.42) | SIGMAR1CHRM1TP53TDP1ACACB | |
| SCHEMBL4474136 | 0.80 | SIGMAR1 (0.43) | MEN1KMT2AKDM4ECYP2C9CYP2C19 | |
| SCHEMBL12606996 | 0.80 | SIGMAR1 (0.43) | SIGMAR1ACACBACACAL3MBTL3L3MBTL1 | |
| SCHEMBL4678853 | 0.79 | L3MBTL3 (0.50) | CPN1CPB2KDM4ECYP2C9CYP2C19 | |
| SCHEMBL26138783 | 0.79 | SIGMAR1 (0.42) | MEN1KMT2AKDM4ESIGMAR1CHRM1 | |
| SCHEMBL25856485 | 0.79 | ALDH1A1 (0.53) | MEN1KMT2ACPN1CPB2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170218000-A1 | PHOSPHOROUS DERIVATIVES AS KINASE INHIBITORS | ARIAD PHARMACEUTICALS, INC. | 2017-08-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170218000-A1 | PHOSPHOROUS DERIVATIVES AS KINASE INHIBITORS | MAP3K6, PIK3CA, MAP3K20 | MEN1 826/4885KMT2A 1452/4885CPN1 1838/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.