Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 2/20 | 0.35 |
| ▸ | MGLL | Q99685 | 2/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 5/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 5/20 | 0.33 |
| ▸ | ADRB3 | P13945 | 5/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7017228 | 0.76 | ALDH1A1 (0.41) | ALDH1A1LMNACYP24A1FAAHMGLL | |
| SCHEMBL3732955 | 0.74 | KMT2A (0.36) | LMNAKMT2AHTTSMN1; SMN2 | |
| SCHEMBL28277861 | 0.73 | PARP1 (0.39) | ALDH1A1LMNAKMT2A | |
| SCHEMBL9316350 | 0.71 | KMT2A (0.34) | KMT2A | |
| SCHEMBL1325 | 0.71 | FAAH (0.45) | ALDH1A1LMNACYP24A1FAAHMGLL | |
| SCHEMBL15846673 | 0.71 | FAAH (0.45) | ALDH1A1LMNACYP24A1FAAHMGLL | |
| SCHEMBL2194853 | 0.69 | FAAH (0.44) | ALDH1A1LMNACYP24A1FAAHMGLL | |
| Phosphine SCHEMBL31680518 | 0.69 | FAAH (0.44) | ALDH1A1LMNACYP24A1FAAHMGLL | |
| Hydrogen Sulfide SCHEMBL10814521 | 0.69 | FAAH (0.44) | ALDH1A1LMNACYP24A1FAAHMGLL | |
| SCHEMBL10814524 | 0.69 | FAAH (0.44) | ALDH1A1LMNACYP24A1FAAHMGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10010556-B2 | Bicyclic bromodomain inhibitors | ZENITH EPIGENETICS LTD. (CA) | 2018-07-03 | — | — | US | disclosed |
| US-20170216301-A1 | NOVEL BICYCLIC BROMODOMAIN INHIBITORS | ZENITH EPIGENETICS LTD. | 2017-08-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10010556-B2 | Bicyclic bromodomain inhibitors | BRD4, BRD3, BRD2 | ALDH1A1 4510/4885LMNA 1910/4885CYP24A1 3749/4885 |
| US-20170216301-A1 | NOVEL BICYCLIC BROMODOMAIN INHIBITORS | BRD4, BRD3, BRD2 | ALDH1A1 4568/4885LMNA 2013/4885CYP24A1 3785/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.