Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 2/20 | 0.38 |
| ▸ | MGLL | Q99685 | 2/20 | 0.38 |
| ▸ | ALPL | P05186 | 2/20 | 0.33 |
| ▸ | ALPG | P10696 | 2/20 | 0.33 |
| ▸ | ALPI | P09923 | 1/20 | 0.33 |
| ▸ | PLAA | Q9Y263 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.33 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.33 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.33 |
| ▸ | AHR | P35869 | 1/20 | 0.32 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL309967 | 0.83 | FDPS (0.39) | ALDH1A1ALPLALPGALPIPLAA | |
| SCHEMBL15846673 | 0.79 | FAAH (0.45) | ALDH1A1LMNAFAAHMGLLCYP24A1 | |
| SCHEMBL1325 | 0.79 | FAAH (0.45) | ALDH1A1LMNAFAAHMGLLCYP24A1 | |
| Hydrogen Sulfide SCHEMBL10814521 | 0.77 | FAAH (0.44) | ALDH1A1LMNAFAAHMGLLCYP24A1 | |
| Hydrochloric Acid SCHEMBL6226784 | 0.77 | FAAH (0.44) | ALDH1A1LMNAFAAHMGLLALPG | |
| SCHEMBL10814524 | 0.77 | FAAH (0.44) | ALDH1A1LMNAFAAHMGLLCYP24A1 | |
| SCHEMBL2194853 | 0.77 | FAAH (0.44) | ALDH1A1LMNAFAAHMGLLCYP24A1 | |
| Phosphine SCHEMBL31680518 | 0.77 | FAAH (0.44) | ALDH1A1LMNAFAAHMGLLCYP24A1 | |
| SCHEMBL19199732 | 0.76 | ALDH1A1 (0.36) | ALDH1A1LMNAFAAHMGLLADRB2 | |
| Methylene Chloride SCHEMBL4130957 | 0.71 | ALDH1A1 (0.42) | ALDH1A1LMNAFAAHMGLLMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1204663-B1 | NOVEL SPIRO COMPOUNDS WITH NEUROPEPTIDE Y ANTAGONISTIC ACTIVITY | BANYU PHARMA CO LTD (JP) | 2003-10-29 | — | — | EP | disclosed |