Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO1 | P15559 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
| ▸ | CASP7 | P55210 | 1/20 | 0.50 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.47 |
| ▸ | TTR | P02766 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | CASP6 | P55212 | 2/20 | 0.40 |
| ▸ | NSD2 | O96028 | 1/20 | 0.40 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.40 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | AURKA | O14965 | 1/20 | 0.39 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.39 |
| ▸ | NT5E | P21589 | 3/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1224928 | 0.85 | PGAM1 (0.53) | NQO1ALDH1A1HSD17B10TDP1CASP1 | |
| SCHEMBL28145555 | 0.82 | PGAM1 (0.52) | NQO1ALDH1A1HSD17B10TDP1CASP1 | |
| SCHEMBL28146678 | 0.82 | PGAM1 (0.52) | NQO1ALDH1A1HSD17B10TDP1CASP1 | |
| SCHEMBL1412987 | 0.79 | TTR (0.46) | NQO1ALDH1A1HSD17B10TDP1CASP1 | |
| SCHEMBL10881182 | 0.79 | ALDH1A1 (0.63) | NQO1ALDH1A1HSD17B10TDP1CASP1 | |
| SCHEMBL27800252 | 0.79 | AURKA (0.50) | NQO1ALDH1A1HSD17B10TDP1CASP1 | |
| SCHEMBL11127906 | 0.79 | NQO1 (0.78) | NQO1ALDH1A1HSD17B10TDP1CASP1 | |
| SCHEMBL9174627 | 0.79 | NQO1 (0.78) | NQO1ALDH1A1HSD17B10TDP1CASP1 | |
| SCHEMBL669090 | 0.78 | PGAM1 (0.48) | NQO1ALDH1A1HSD17B10TDP1CASP1 | |
| SCHEMBL8747632 | 0.78 | ALDH1A1 (0.68) | NQO1ALDH1A1HSD17B10TDP1CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017132484-A1 | PHOTO-CLEAVABLE PRIMER COMPOSITIONS AND METHODS OF USE | ACatechol, Inc. (US) | 2017-08-03 | — | — | WO | disclosed |