Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.51 |
| ▸ | NPC1 | O15118 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | YAP1 | P46937 | 1/20 | 0.43 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19181031 | 0.92 | RAB9A (0.53) | RAB9ANPC1SMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL17524121 | 0.92 | RAB9A (0.53) | RAB9ANPC1SMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL19181334 | 0.87 | LMNA (0.59) | RAB9ANPC1ALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL17523976 | 0.87 | LMNA (0.59) | RAB9ANPC1ALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL17505996 | 0.83 | RAB9A (0.58) | RAB9ANPC1SMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL17505997 | 0.83 | RAB9A (0.58) | RAB9ANPC1SMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL19200748 | 0.80 | SMN1; SMN2 (0.50) | RAB9ANPC1SMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL17524125 | 0.79 | RAB9A (0.55) | RAB9ANPC1SMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL17506011 | 0.78 | CASR (0.57) | RAB9ANPC1ALDH1A1LMNAMAPT | |
| SCHEMBL17506010 | 0.78 | CASR (0.57) | RAB9ANPC1ALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170217914-A1 | Novel Triarylethylene Compounds and Methods Using Same | THE PENN STATE RESEARCH FOUNDATION | 2017-08-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170217914-A1 | Novel Triarylethylene Compounds and Methods Using Same | CYP46A1, GSTA2, GSTA1 | RAB9A 2537/4885NPC1 23/4885SMN1; SMN2 3107/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.