Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | MAPT | P10636 | 7/20 | 0.46 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.46 |
| ▸ | ALDH1A3 | P47895 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.43 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15871966 | 0.98 | MAPT (0.49) | ALDH1A1MAPTMCOLN3ALDH1A3TP53 | |
| SCHEMBL13326993 | 0.87 | MEN1 (0.47) | ALDH1A1MAPTMCOLN3ALDH1A3TP53 | |
| SCHEMBL12072936 | 0.86 | HTR1A (0.51) | ALDH1A1MAPTMEN1KMT2ATHRB | |
| SCHEMBL19446858 | 0.84 | HTR1A (0.53) | — | |
| Hydrochloric Acid SCHEMBL2366257 | 0.83 | HTR1A (0.54) | — | |
| SCHEMBL16793166 | 0.82 | NCF1 (0.46) | ALDH1A1MAPTMCOLN3ALDH1A3TP53 | |
| SCHEMBL23440705 | 0.80 | HPGD (0.51) | ALDH1A1MAPTALDH1A3TP53MEN1 | |
| SCHEMBL22350739 | 0.80 | ALDH1A1 (0.53) | ALDH1A1MCOLN3ALDH1A3MEN1KMT2A | |
| SCHEMBL15509139 | 0.80 | MAPT (0.59) | ALDH1A1MAPTALDH1A3MEN1KMT2A | |
| SCHEMBL23473245 | 0.79 | TP53 (0.36) | ALDH1A1MAPTTP53MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017132173-A1 | MAYTANSINOID DERIVATIVES, CONJUGATES THEREOF, AND METHODS OF USE | REGENERON PHARMACEUTICALS, INC. (US) | 2017-08-03 | — | — | WO | disclosed |