Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | THRB | P10828 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | SETDB1 | Q15047 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19203563 | 0.79 | ALDH1A1 (0.46) | TP53MAPTKMT2AMEN1TSHR | |
| SCHEMBL15871966 | 0.77 | MAPT (0.49) | TP53MAPTKMT2AMEN1TSHR | |
| SCHEMBL12072936 | 0.76 | HTR1A (0.51) | MAPTKMT2AMEN1TSHRALDH1A1 | |
| SCHEMBL19446858 | 0.75 | HTR1A (0.53) | DRD2DRD4 | |
| Hydrochloric Acid SCHEMBL2366257 | 0.73 | HTR1A (0.54) | DRD2DRD4 | |
| SCHEMBL20457971 | 0.71 | GAA (0.44) | MAPTKMT2AMEN1TSHRALDH1A1 | |
| SCHEMBL12826415 | 0.69 | NPSR1 (0.46) | MAPTTSHRALDH1A1LMNAHPGD | |
| SCHEMBL19144322 | 0.69 | KDM4E (0.46) | TP53MAPTAADATKMT2AMEN1 | |
| SCHEMBL18436540 | 0.69 | ALDH1A1 (0.45) | TP53MAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL2366253 | 0.68 | LMNA (0.62) | MAPTKMT2AMEN1TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3831378-A1 | SIPONIMOD IMMEDIATE RELEASE DOSAGE REGIMEN FOR TREATING AUTOIMMUNE DISEASES | Novartis AG (CH) | 2021-06-09 | — | — | EP | disclosed |